catalog number :
MBS9337146
products type :
ELISA Kit
products full name :
Human SET and MYND domain-containing protein 3, SMYD3 ELISA Kit
products short name :
[SET and MYND domain containing 3]
products name syn :
[Human SET and MYND domain-containing protein 3 (SMYD3) ELISA kit; FLJ21080; MGC104324; ZMYND1; ZNFN3A1; bA74P14.1; bA74P14.1 (novel protein) ; zinc finger protein; subfamily 3A (MYND domain containing); 1; zinc finger; MYND domain containing 1; SET and MYND domain containing 3]
other names :
[histone-lysine N-methyltransferase SMYD3 isoform 1; Histone-lysine N-methyltransferase SMYD3; histone-lysine N-methyltransferase SMYD3; bA74P14.1 (novel protein); zinc finger, MYND domain containing 1; SET and MYND domain-containing protein 3; zinc finger MYND domain-containing protein 1; zinc finger protein, subfamily 3A (MYND domain containing), 1; SET and MYND domain containing 3; SET and MYND domain-containing protein 3; Zinc finger MYND domain-containing protein 1]
products gene name :
[SMYD3]
other gene names :
[SMYD3; SMYD3; KMT3E; ZMYND1; ZNFN3A1; bA74P14.1; ZMYND1; ZNFN3A1]
uniprot entry name :
SMYD3_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SMYD3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001161212.1
ncbi gb acc num :
NM_001167740.1
ncbi mol weight :
49,097 Da
ncbi summary :
This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
uniprot summary :
SMYD3: Histone methyltransferase. Specifically methylates Lys- 4 of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5 -CCCTCC-3 or 5 -GAGGGG-3 sequences. Belongs to the histone-lysine methyltransferase family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Methyltransferase, protein lysine; Methyltransferase; EC 2.1.1.43. Chromosomal Location of Human Ortholog: 1q44. Cellular Component: nucleoplasm; cytoplasm. Molecular Function: metal ion binding; histone-lysine N-methyltransferase activity. Biological Process: nucleosome assembly; establishment of protein localization; establishment and/or maintenance of chromatin architecture; myotube cell development; negative regulation of protein kinase activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of peptidyl-serine phosphorylation
size4 :
10x96-Strip-Wells