catalog number :
MBS9337037
products type :
ELISA Kit
products full name :
Human Grancalcin, GCA ELISA Kit
products short name :
[grancalcin, EF-hand calcium binding protein]
products name syn :
[Human Grancalcin (GCA) ELISA kit; GCL; grancalcin; EF-hand calcium-binding protein; grancalcin; penta-EF-hand protein; grancalcin; EF-hand calcium binding protein]
other names :
[grancalcin; Grancalcin; grancalcin; grancalcin, penta-EF-hand protein; grancalcin, EF-hand calcium-binding protein; grancalcin, EF-hand calcium binding protein]
products gene name :
[GCA]
other gene names :
[GCA; GCA; GCL; GCL]
uniprot entry name :
GRAN_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Monkey Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 25pg/ml-800pg/ml. Sensitivity: 2.0pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of GC (hereafter termed "analyte") in undiluted original Monkey body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_036330.1
ncbi gb acc num :
NM_012198.3
ncbi mol weight :
24,010 Da
ncbi summary :
This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation. [provided by RefSeq, Jul 2008]
uniprot summary :
GCA: Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions. Protein type: Calcium-binding. Chromosomal Location of Human Ortholog: 2q24.2. Cellular Component: cytoplasm; plasma membrane. Molecular Function: protein homodimerization activity; protein heterodimerization activity; calcium-dependent cysteine-type endopeptidase activity; calcium ion binding. Biological Process: proteolysis
size4 :
10x96-Strip-Wells