ELISA/assay

Human fMet-Leu-Phe receptor, FPR1 ELISA Kit

MBS9336637

48-Strip-Wells

470 USD

ELISA Kit

Human fMet-Leu-Phe receptor, FPR1 ELISA Kit

[formyl peptide receptor 1]

[Human fMet-Leu-Phe receptor (FPR1) ELISA kit; FMLP; FPR; ; formyl peptide receptor 1]

[fMet-Leu-Phe receptor; fMet-Leu-Phe receptor; fMet-Leu-Phe receptor; fMLP receptor; N-formylpeptide chemoattractant receptor; formyl peptide receptor 1; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor]

[FPR1]

[FPR1; FPR1; FPR; FMLP; fMLP receptor; FPR]

FPR1_HUMAN

Human

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Mouse Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

Intra-assay Precision: Intra-assay CV (%)is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of FPN (hereafter termed "analyte") in undiluted original Mouse body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

300863094

NP_001180235.1

NM_001193306.1

P21462

38,446 Da

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway (161021); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Peptide GPCRs Pathway (198897); Peptide Ligand-binding Receptors Pathway (106358)

This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010]

FPR1: High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 19q13.4. Cellular Component: plasma membrane; integral to membrane; endosome. Molecular Function: protein binding; RAGE receptor binding; N-formyl peptide receptor activity; receptor activity. Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor protein signaling pathway; activation of MAPK activity; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); chemotaxis; signal transduction; cell motility; nitric oxide mediated signal transduction

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095