Human Proteasome subunit alpha type-3, PSMA3 ELISA Kit | MyBioSource MBS9336584 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Proteasome subunit alpha type-3, PSMA3 ELISA Kit

catalog :

MBS9336584

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9336584

products type :

ELISA Kit

products full name :

Human Proteasome subunit alpha type-3, PSMA3 ELISA Kit

products short name :

[proteasome (prosome, macropain) subunit, alpha type, 3]

products name syn :

[Human Proteasome subunit alpha type-3 (PSMA3) ELISA kit; HC8; MGC12306; MGC32631; PSC3; macropain subunit C8; multicatalytic endopeptidase complex subunit C8; proteasome alpha 3 subunit; proteasome subunit C8; proteasome (prosome; macropain) subunit; alpha type; 3]

other names :

[proteasome subunit alpha type-3 isoform 1; Proteasome subunit alpha type-3; proteasome subunit alpha type-3; macropain subunit C8; proteasome subunit C8; proteasome component C8; multicatalytic endopeptidase complex subunit C8; proteasome (prosome, macropain) subunit, alpha type, 3; Macropain subunit C8; Multicatalytic endopeptidase complex subunit C8; Proteasome component C8]

products gene name :

[PSMA3]

other gene names :

[PSMA3; PSMA3; HC8; PSC3; HC8; PSC8]

uniprot entry name :

PSA3_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PSMA3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

4506183

ncbi acc num :

NP_002779.1

ncbi gb acc num :

NM_002788.3

uniprot acc num :

P25788

ncbi mol weight :

28,433 Da

ncbi pathways :

APC/C-mediated Degradation Of Cell Cycle Proteins Pathway (105825); APC/C:Cdc20 Mediated Degradation Of Securin Pathway (105833); APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway (105831); APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway (105835); Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway (105829); Activation Of NF-kappaB In B Cells Pathway (576251); Adaptive Immune System Pathway (366160); Antigen Processing-Cross Presentation Pathway (477122); Antigen Processing: Ubiquitination Proteasome Degradation Pathway (366162); Apoptosis Pathway (105648)

ncbi summary :

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

uniprot summary :

PSMA3: a proteasomal protein of the T1A peptidase family. The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. Two alternatively spliced isoforms have been identified. Protein type: Protease; EC 3.4.25.1; Proteasome complex. Chromosomal Location of Human Ortholog: 14q23. Cellular Component: proteasome complex; nucleoplasm; proteasome core complex; cytoplasm; cytosol; nucleus. Molecular Function: threonine endopeptidase activity; protein binding. Biological Process: positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; protein polyubiquitination; viral reproduction; apoptosis; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; regulation of apoptosis; antigen processing and presentation of peptide antigen via MHC class I; regulation of ubiquitin-protein ligase activity during mitotic cell cycle; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; gene expression; mitotic cell cycle; regulation of amino acid metabolic process; G1/S transition of mitotic cell cycle; negative regulation of apoptosis

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095