Human Farnesyl pyrophosphate synthase, FDPS ELISA Kit | MyBioSource MBS9336350 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Farnesyl pyrophosphate synthase, FDPS ELISA Kit

catalog :

MBS9336350

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9336350

products type :

ELISA Kit

products full name :

Human Farnesyl pyrophosphate synthase, FDPS ELISA Kit

products short name :

farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)

products name syn :

Human Farnesyl pyrophosphate synthase (FDPS) ELISA kit; FPPS; FPS; FPP synthetase; dimethylallyltranstransferase; farnesyl diphosphate synthase; farnesyl pyrophosphate synthetase; geranyltranstransferase; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase; dimethylallyltranstransferase; geranyltranstransferase)

other names :

farnesyl pyrophosphate synthase isoform a; Farnesyl pyrophosphate synthase; farnesyl pyrophosphate synthase; FPP synthase; FPP synthetase; geranyltranstransferase; dimethylallyltranstransferase; (2E,6E)-farnesyl diphosphate synthase; farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase; farnesyl diphosphate synthase; (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase (EC:2.5.1.1); Farnesyl diphosphate synthase; Geranyltranstransferase

products gene name :

FDPS

other gene names :

FDPS; FDPS; FPS; FPPS; FPS; KIAA1293; FPP synthase; FPS

uniprot entry name :

FPPS_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of FDPS (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

209571582

ncbi acc num :

NP_001129293.1

ncbi gb acc num :

NM_001135821.1

uniprot acc num :

P14324

ncbi mol weight :

48,275 Da

ncbi pathways :

Cholesterol Biosynthesis Pathway (198809); Cholesterol Biosynthesis Pathway (106142); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); Influenza A Pathway (217173); Influenza A Pathway (217150); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Terpenoid Backbone Biosynthesis Pathway (83022); Terpenoid Backbone Biosynthesis Pathway (408)

ncbi summary :

This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]

uniprot summary :

FDPS: Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. Belongs to the FPP/GGPP synthase family. Protein type: Motility/polarity/chemotaxis; Transferase; EC 2.5.1.10; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; EC 2.5.1.1. Chromosomal Location of Human Ortholog: 1q22. Cellular Component: nucleoplasm; mitochondrion; cytoplasm; cytosol. Molecular Function: geranyltranstransferase activity; dimethylallyltranstransferase activity; metal ion binding. Biological Process: viral reproduction; geranyl diphosphate biosynthetic process; farnesyl diphosphate biosynthetic process; cholesterol biosynthetic process

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage