product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human RING finger protein 43, RNF43 ELISA Kit
catalog :
MBS9336145
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9336145
products type :
ELISA Kit
products full name :
Human RING finger protein 43, RNF43 ELISA Kit
products short name :
[ring finger protein 43]
products name syn :
[Human RING finger protein 43 (RNF43) ELISA kit; DKFZp781H02126; DKFZp781H0392; FLJ20315; FLJ77466; FLJ99338; MGC125630; RNF124; URCC; ; ring finger protein 43]
other names :
[E3 ubiquitin-protein ligase RNF43; E3 ubiquitin-protein ligase RNF43; E3 ubiquitin-protein ligase RNF43; ring finger protein 43; RING finger protein 43]
products gene name :
[RNF43]
other gene names :
[RNF43; RNF43; URCC; RNF124]
uniprot entry name :
RNF43_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 31.2pg/ml-1000pg/ml. Sensitivity: 5.0pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) are less than 15%. Inter-assay Precision: Inter-assay CV (?) are less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of RNF145 (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
56711322
ncbi acc num :
NP_060233.3
ncbi gb acc num :
NM_017763.4
uniprot acc num :
Q68DV7
ncbi mol weight :
85,722 Da
ncbi summary :
RNF43 is a HAP95 (AKAP8L; MIM 609475) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer (Yagyu et al., 2004 [PubMed 15492824]; Sugiura et al., 2008 [PubMed 18313049]).[supplied by OMIM, Dec 2008]
uniprot summary :
RNF43: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. Belongs to the ZNRF3 family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Ubiquitin conjugating system; Membrane protein, integral; Ligase; Ubiquitin ligase; EC 6.3.2.-. Chromosomal Location of Human Ortholog: 17q22. Cellular Component: endoplasmic reticulum membrane; integral to plasma membrane; plasma membrane; nuclear envelope. Molecular Function: protein binding; zinc ion binding; frizzled binding; ubiquitin-protein ligase activity; ligase activity. Biological Process: negative regulation of Wnt receptor signaling pathway; Wnt receptor signaling pathway; protein ubiquitination during ubiquitin-dependent protein catabolic process; protein ubiquitination
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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