catalog number :
MBS9336143
products type :
ELISA Kit
products full name :
Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1, GFPT1 ELISA Kit
products short name :
[glutamine-fructose-6-phosphate transaminase 1]
products name syn :
[Human Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) ELISA kit; GFA; GFAT; GFAT1; GFAT1m; GFPT; glucosamine-fructose-6-phosphate aminotransferase; glutamine: fructose-6-phosphate amidotransferase-1; glutamine-fructose-6-phosphate transaminase 1]
other names :
[glutamine--fructose-6-phosphate aminotransferase; Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1; glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1; glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1; hexosephosphate aminotransferase 1; D-fructose-6-phosphate amidotransferase 1; glutamine:fructose-6-phosphate amidotransferase 1; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1; glutamine--fructose-6-phosphate transaminase 1; D-fructose-6-phosphate amidotransferase 1; Glutamine:fructose-6-phosphate amidotransferase 1; GFAT 1; GFAT1; Hexosephosphate aminotransferase 1]
products gene name :
[GFPT1]
other gene names :
[GFPT1; GFPT1; GFA; GFAT; GFPT; MSLG; GFAT1; CMSTA1; GFAT 1; GFAT1m; GFPT1L; GFAT; GFPT; GFAT 1; GFAT1]
uniprot entry name :
GFPT1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GFPT1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001231639.1
ncbi gb acc num :
NM_001244710.1
ncbi mol weight :
78,806 Da
ncbi pathways :
Activation Of Chaperone Genes By XBP1(S) Pathway (530771); Activation Of Chaperones By IRE1alpha Pathway (105906); Alanine, Aspartate And Glutamate Metabolism Pathway (101142); Alanine, Aspartate And Glutamate Metabolism Pathway (100063); Amino Sugar And Nucleotide Sugar Metabolism Pathway (82979); Amino Sugar And Nucleotide Sugar Metabolism Pathway (350); Asparagine N-linked Glycosylation Pathway (161013); Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway (161014); Diabetes Pathways (105902); Disease Pathway (530764)
ncbi summary :
This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate. [provided by RefSeq, Sep 2008]
uniprot summary :
GFAT: Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Homotetramer (Potential). Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 2.6.1.16; Amino Acid Metabolism - alanine, aspartate and glutamate; Transferase; Carbohydrate Metabolism - amino sugar and nucleotide sugar. Chromosomal Location of Human Ortholog: 2p13. Cellular Component: cytosol. Molecular Function: amino acid binding; carbohydrate binding; glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Biological Process: dolichol-linked oligosaccharide biosynthetic process; unfolded protein response; glucosamine biosynthetic process; glutamine metabolic process; fructose 6-phosphate metabolic process; post-translational protein modification; carbohydrate biosynthetic process; protein homotetramerization; response to sucrose stimulus; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; cellular response to insulin stimulus; energy reserve metabolic process; UDP-N-acetylglucosamine biosynthetic process; protein amino acid N-linked glycosylation via asparagine; circadian regulation of gene expression; negative regulation of glycogen biosynthetic process. Disease: Myasthenic Syndrome, Congenital, Associated With Acetylcholine Receptor Deficiency; Myasthenic Syndrome, Congenital, With Tubular Aggregates 1
size4 :
10x96-Strip-Wells