catalog number :
MBS9336009
products type :
ELISA Kit
products full name :
Human Histone deacetylase complex subunit SAP130, SAP130 ELISA Kit
products short name :
Sin3A-associated protein, 130kDa
products name syn :
Human Histone deacetylase complex subunit SAP130 (SAP130) ELISA kit; FLJ12761; Sin3-associated polypeptide p130; histone deacetylase complex subunit SAP130; mSin3A-associated protein 130; Sin3A-associated protein; 130kDa
other names :
histone deacetylase complex subunit SAP130 isoform a; Histone deacetylase complex subunit SAP130; histone deacetylase complex subunit SAP130; mSin3A-associated protein 130; Sin3-associated polypeptide p130; 130 kDa Sin3-associated polypeptide; Sin3A-associated protein, 130kDa; 130 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p130
products gene name :
SAP130
other gene names :
SAP130; SAP130
uniprot entry name :
SP130_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 62.5 pg/ml - 2000 pg/ml. Sensitivity: 10 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SAP130 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001139400.1
ncbi gb acc num :
NM_001145928.1
ncbi mol weight :
110,324 Da
ncbi summary :
SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008]
uniprot summary :
SAP130: Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. Belongs to the SAP130 family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription factor; Acetyltransferase. Chromosomal Location of Human Ortholog: 2q14.3. Cellular Component: nucleoplasm. Molecular Function: histone acetyltransferase activity; transcription coactivator activity. Biological Process: establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; negative regulation of gene expression, epigenetic; gene expression; negative regulation of transcription from RNA polymerase II promoter; regulation of gene expression, epigenetic