catalog number :
MBS9335997
products type :
ELISA Kit
products full name :
Human Monocarboxylate transporter 4, SLC16A3 ELISA Kit
products short name :
[solute carrier family 16, member 3 (monocarboxylic acid transporter 4)]
products name syn :
[Human Monocarboxylate transporter 4 (SLC16A3) ELISA kit; MCT3; MCT4; MGC138472; MGC138474; monocarboxylate transporter 3; monocarboxylate transporter 4; solute carrier family 16 (monocarboxylic acid transporters); member 3; solute carrier family 16; member 3; solute carrier family 16; member 3 (monocarboxylic acid transporter 4)]
other names :
[monocarboxylate transporter 4; Monocarboxylate transporter 4; monocarboxylate transporter 4; monocarboxylate transporter 3; solute carrier family 16 (monocarboxylic acid transporters), member 3; solute carrier family 16, member 3 (monocarboxylic acid transporter 4); solute carrier family 16 (monocarboxylate transporter), member 3; Solute carrier family 16 member 3]
products gene name :
[SLC16A3]
other gene names :
[SLC16A3; SLC16A3; MCT3; MCT4; MCT 3; MCT 4; MCT-3; MCT-4; MCT4; MCT 4]
uniprot entry name :
MOT4_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of SLC12A3 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001035887.1
ncbi gb acc num :
NM_001042422.2
ncbi mol weight :
49,469 Da
ncbi pathways :
Basigin Interactions Pathway (106065); Cell Surface Interactions At The Vascular Wall Pathway (106062); Hemostasis Pathway (106028); Metabolism Pathway (477135); Proton-coupled Monocarboxylate Transport Pathway (161065); Pyruvate Metabolism Pathway (106205); Pyruvate Metabolism And Citric Acid (TCA) Cycle Pathway (106327); SLC-mediated Transmembrane Transport Pathway (119558); The Citric Acid (TCA) Cycle And Respiratory Electron Transport Pathway (477137); Transmembrane Transport Of Small Molecules Pathway (106572)
ncbi summary :
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008]
uniprot summary :
SLC16A3: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, SLC family. Chromosomal Location of Human Ortholog: 17q25. Cellular Component: nuclear membrane; membrane; integral to plasma membrane; plasma membrane; actin cytoskeleton. Molecular Function: monocarboxylic acid transmembrane transporter activity; symporter activity; lactate transmembrane transporter activity; secondary active monocarboxylate transmembrane transporter activity. Biological Process: cellular metabolic process; monocarboxylic acid transport; blood coagulation; pyruvate metabolic process; leukocyte migration; transmembrane transport
size4 :
10x96-Strip-Wells