catalog number :
MBS9335658
products type :
ELISA Kit
products full name :
Human Guanylate cyclase soluble subunit beta-1, GUCY1B3 ELISA Kit
products short name :
[guanylate cyclase 1, soluble, beta 3]
products name syn :
[Human Guanylate cyclase soluble subunit beta-1 (GUCY1B3) ELISA kit; GC-S-beta-1; GC-SB3; GUC1B3; GUCB3; GUCSB3; GUCY1B1; ; guanylate cyclase 1; soluble; beta 3]
other names :
[guanylate cyclase soluble subunit beta-1 isoform 2; Guanylate cyclase soluble subunit beta-1; guanylate cyclase soluble subunit beta-1; GCS-beta-1; GCS-beta-3; soluble guanylate cyclase small subunit; guanylate cyclase soluble subunit beta-3; guanylate cyclase 1, soluble, beta 3; Guanylate cyclase soluble subunit beta-3; GCS-beta-3; Soluble guanylate cyclase small subunit]
products gene name :
[GUCY1B3]
other gene names :
[GUCY1B3; GUCY1B3; GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B1; GC-S-beta-1; GUC1B3; GUCSB3; GUCY1B1; GCS-beta-1; GCS-beta-3]
uniprot entry name :
GCYB1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GUCY1B3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_000848.1
ncbi gb acc num :
NM_000857.3
ncbi mol weight :
70,514 Da
ncbi pathways :
Gap Junction Pathway (83072); Gap Junction Pathway (483); Hemostasis Pathway (106028); Long-term Depression Pathway (83086); Long-term Depression Pathway (497); Nitric Oxide Stimulates Guanylate Cyclase Pathway (187200); Platelet Homeostasis Pathway (187198); Purine Metabolism Pathway (82944); Purine Metabolism Pathway (307); Salivary Secretion Pathway (153376)
ncbi summary :
This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
uniprot summary :
GUCY1B3: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Heterodimer of an alpha and a beta chain. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Guanylyl cyclase; Nucleotide Metabolism - purine; Receptor, misc.; Lyase; EC 4.6.1.2. Chromosomal Location of Human Ortholog: 4q31.3-q33. Cellular Component: guanylate cyclase complex, soluble; intracellular membrane-bound organelle; cytoplasm. Molecular Function: guanylate cyclase activity; GTP binding; protein heterodimerization activity; metal ion binding; heme binding; receptor activity; Hsp90 protein binding. Biological Process: cGMP biosynthetic process; blood circulation; blood coagulation; nitric oxide mediated signal transduction
size4 :
10x96-Strip-Wells