catalog number :
MBS9335594
products type :
ELISA Kit
products full name :
Human Thrombospondin type-1 domain-containing protein 7A, THSD7A ELISA Kit
products short name :
thrombospondin, type I, domain containing 7A
products name syn :
Human Thrombospondin type-1 domain-containing protein 7A (THSD7A) ELISA kit; KIAA0960; ; thrombospondin; type I; domain containing 7A
other names :
thrombospondin type-1 domain-containing protein 7A; Thrombospondin type-1 domain-containing protein 7A; thrombospondin type-1 domain-containing protein 7A; thrombospondin, type I, domain containing 7A
products gene name :
THSD7A
other gene names :
THSD7A; THSD7A; KIAA0960
uniprot entry name :
THS7A_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml. Assay Type: Sandwich
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of THSD7A (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_056019.1
ncbi gb acc num :
NM_015204.2
ncbi mol weight :
185,363 Da
ncbi summary :
The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be associated with low bone mineral density in osteoporosis. [provided by RefSeq, Aug 2010]
uniprot summary :
THSD7A: The soluble form promotes endothelial cell migration and filopodia formationduring angiogenesis via a FAK-dependent mechanism. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 7p21.3. Cellular Component: integral to membrane; plasma membrane. Biological Process: angiogenesis; cell differentiation