ELISA/assay

Human Mitogen-activated protein kinase kinase kinase kinase 1, MAP4K1 ELISA Kit

MBS9335513

48-Strip-Wells

470 USD

ELISA Kit

Human Mitogen-activated protein kinase kinase kinase kinase 1, MAP4K1 ELISA Kit

[mitogen-activated protein kinase kinase kinase kinase 1]

[Human Mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1) ELISA kit; HPK1; hematopoietic progenitor kinase 1; mitogen-activated protein kinase kinase kinase kinase 1]

[mitogen-activated protein kinase kinase kinase kinase 1 isoform 1; Mitogen-activated protein kinase kinase kinase kinase 1; mitogen-activated protein kinase kinase kinase kinase 1; MEKKK 1; MEK kinase kinase 1; MAPK/ERK kinase kinase kinase 1; hematopoietic progenitor kinase 1; mitogen-activated protein kinase kinase kinase kinase 1; Hematopoietic progenitor kinase; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1]

[MAP4K1]

[MAP4K1; MAP4K1; HPK1; HPK1; MEK kinase kinase 1; MEKKK 1]

M4K1_HUMAN

Human

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Human Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.5ng/ml-16ng/ml. Sensitivity: 0.1ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of MAP3K14 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

110611908

NP_001036065.1

NM_001042600.2

Q92918

91,296 Da

B Cell Receptor Signaling Pathway (198909); BCR Signaling Pathway (138058); Insulin Signaling Pathway (198845); JNK Signaling In The CD4+ TCR Pathway (138066); MAPK Signaling Pathway (198779); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Prostate Cancer Pathway (755440); Signaling Events Mediated By Stem Cell Factor Receptor (c-Kit) Pathway (138068); Signaling Of Hepatocyte Growth Factor Receptor Pathway (198836)

HPK1: a protein kinase of the STE20 family. Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine. May play a role in hematopoietic lineage decisions and growth regulation. Positively regulated by PGE2 and a negative regulator of PGE2-induced FOS gene transcription. Protein type: Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Protein kinase, STE; STE group; STE20 family; KHS subfamily. Chromosomal Location of Human Ortholog: 19q13.1-q13.4. Cellular Component: membrane; cytoplasm. Molecular Function: protein serine/threonine kinase activity; protein binding; MAP kinase kinase kinase kinase activity; ATP binding; protein kinase activity. Biological Process: cell proliferation; peptidyl-serine phosphorylation; protein amino acid autophosphorylation; activation of MAPKKK activity; response to stress; protein amino acid phosphorylation; activation of JNK activity

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095