Human Transforming protein RhoA, RHOA ELISA Kit | MyBioSource MBS9335451 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Transforming protein RhoA, RHOA ELISA Kit

catalog :

MBS9335451

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9335451

products type :

ELISA Kit

products full name :

Human Transforming protein RhoA, RHOA ELISA Kit

products short name :

ras homolog gene family, member A

products name syn :

Human Transforming protein RhoA (RHOA) ELISA kit; ARH12; ARHA; RHO12; RHOH12; Aplysia ras-related homolog 12; oncogene RHO H12; small GTP binding protein RhoA; ras homolog gene family; member A

other names :

transforming protein RhoA; Transforming protein RhoA; transforming protein RhoA; h12; oncogene RHO H12; rho cDNA clone 12; Aplysia ras-related homolog 12; small GTP binding protein RhoA; ras homolog gene family, member A; ras homolog family member A; Rho cDNA clone 12; h12

products gene name :

RHOA

other gene names :

RHOA; RHOA; ARHA; ARH12; RHO12; RHOH12; ARH12; ARHA; RHO12; h12

uniprot entry name :

RHOA_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RHOA (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

10835049

ncbi acc num :

NP_001655.1

ncbi gb acc num :

NM_001664.2

uniprot acc num :

P61586

ncbi mol weight :

21,768 Da

ncbi pathways :

AGE/RAGE Pathway (698754); Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Alpha6-Beta4 Integrin Signaling Pathway (198807); Androgen Receptor Signaling Pathway (198806); Arf6 Downstream Pathway (138038); Aurora B Signaling Pathway (138080); Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (105688)

ncbi summary :

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]

uniprot summary :

RHOA: a small G protein of the Rho family. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Controls the reorganization of actins into podosomes. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Protein type: G protein, monomeric; G protein, monomeric, Rho; Motility/polarity/chemotaxis; Oncoprotein; G protein. Chromosomal Location of Human Ortholog: 3p21.3. Cellular Component: apical junction complex; cytoskeleton; focal adhesion; lamellipodium; plasma membrane; midbody; cell cortex; cell junction; cytosol; cleavage furrow. Molecular Function: GTPase activity; protein binding; GTP binding; myosin binding. Biological Process: axon guidance; viral reproduction; nerve growth factor receptor signaling pathway; metabolic process; negative chemotaxis; positive regulation of NF-kappaB import into nucleus; regulation of axonogenesis; regulation of cell migration; Rho protein signal transduction; regulation of osteoblast proliferation; substantia nigra development; small GTPase mediated signal transduction; transforming growth factor beta receptor signaling pathway; positive regulation of stress fiber formation; ephrin receptor signaling pathway; negative regulation of axonogenesis; positive regulation of cytokinesis; platelet activation; apical junction assembly; positive regulation of I-kappaB kinase/NF-kappaB cascade; phosphoinositide-mediated signaling; regulation of small GTPase mediated signal transduction; positive regulation of axonogenesis; actin cytoskeleton organization and biogenesis; blood coagulation; positive regulation of neuron differentiation; vascular endothelial growth factor receptor signaling pathway

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage