catalog number :
MBS9335274
products type :
ELISA Kit
products full name :
Rat Sodium/iodide cotransporter, SLC5A5 ELISA Kit
products short name :
[solute carrier family 5 (sodium iodide symporter) , member 5]
products name syn :
[Rat Sodium/iodide cotransporter (SLC5A5) ELISA kit; NIS; TDH1; Na (+) /I (-) cotransporter; solute carrier family 5 (sodium iodide symporter); member 5]
other names :
[sodium/iodide cotransporter; Sodium/iodide cotransporter; sodium/iodide cotransporter; Na+/I- symporter; Na(+)/I(-) symporter; Na(+)/I(-)-symporter; sodium-iodide symporter; Na(+)/I(-) cotransporter; solute carrier family 5, member 5; solute carrier family 5 (sodium iodide symporter), member 5; solute carrier family 5 (sodium/iodide cotransporter), member 5; Sodium-iodide symporter; Na(+)/I(-) symporter; Solute carrier family 5 member 5]
products gene name :
[SLC5A5]
other gene names :
[Slc5a5; Slc5a5; Nis; Nis; Na(+)/I(-) cotransporter; Na(+)/I(-) symporter]
uniprot entry name :
SC5A5_RAT
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SLC5A5 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_443215.2
ncbi gb acc num :
NM_052983.2
ncbi mol weight :
65,196 Da
ncbi pathways :
Amine-derived Hormones Pathway (1010837); Metabolism Pathway (1010675); Metabolism Of Amino Acids And Derivatives Pathway (1010820); Organic Anion Transporters Pathway (1009977); SLC-mediated Transmembrane Transport Pathway (1009967); Thyroid Hormone Synthesis Pathway (835447); Thyroid Hormone Synthesis Pathway (839541); Thyroxine Biosynthesis Pathway (1010839); Transmembrane Transport Of Small Molecules Pathway (1009963); Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway (1009968)
ncbi summary :
catalyzes Na+/I- symporter activity; plays a role in iodide transport and thyroid hormone generation [RGD, Feb 2006]
uniprot summary :
SLC5A5: Mediates iodide uptake in the thyroid gland. Defects in SLC5A5 are the cause of thyroid dyshormonogenesis 1 (TDH1). A disorder characterized by the inability of the thyroid to maintain a concentration difference of readily exchangeable iodine between the plasma and the thyroid gland, leading to congenital hypothyroidism. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, SLC family. Cellular Component: plasma membrane; integral to membrane; nucleus; vesicle. Molecular Function: iodide transmembrane transporter activity; sodium:iodide symporter activity; symporter activity. Biological Process: iodide transport; sodium ion transport; thyroid hormone generation; anion transport
size4 :
10x96-Strip-Wells