Human Heart- and neural crest derivatives-expressed protein 2, HAND2 ELISA Kit | MyBioSource MBS9335109 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Heart- and neural crest derivatives-expressed protein 2, HAND2 ELISA Kit

catalog :

MBS9335109

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9335109

products type :

ELISA Kit

products full name :

Human Heart- and neural crest derivatives-expressed protein 2, HAND2 ELISA Kit

products short name :

[heart and neural crest derivatives expressed 2]

products name syn :

[Human Heart- and neural crest derivatives-expressed protein 2 (HAND2) ELISA kit; DHAND2; FLJ16260; Hed; MGC125303; MGC125304; Thing2; bHLHa26; dHand; basic helix-loop-helix transcription factor HAND2; heart and neural crest derivatives expressed 2]

other names :

[heart- and neural crest derivatives-expressed protein 2; Heart- and neural crest derivatives-expressed protein 2; heart- and neural crest derivatives-expressed protein 2; class A basic helix-loop-helix protein 26; basic helix-loop-helix transcription factor HAND2; deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2; heart and neural crest derivatives expressed 2; Class A basic helix-loop-helix protein 26; bHLHa26; Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2; dHAND]

products gene name :

[HAND2]

other gene names :

[HAND2; HAND2; Hed; dHand; DHAND2; Thing2; bHLHa26; BHLHA26; DHAND; bHLHa26; dHAND]

uniprot entry name :

HAND2_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma and Tissue Homogenate. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml. Assay Type: Sandwich

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HAND2 (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.

ncbi gi num :

12545384

ncbi acc num :

NP_068808.1

ncbi gb acc num :

NM_021973.2

uniprot acc num :

P61296

ncbi mol weight :

23,666 Da

ncbi pathways :

Heart Development Pathway (198802)

ncbi summary :

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development. [provided by RefSeq, Jul 2008]

uniprot summary :

HAND2: Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5 -CANNTG-3 . Protein type: Transcription factor; DNA-binding. Chromosomal Location of Human Ortholog: 4q33. Cellular Component: transcription factor complex; protein complex; nuclear chromatin. Molecular Function: protein binding; protein homodimerization activity; transcription activator binding; AT DNA binding; protein heterodimerization activity; transcription coactivator activity; transcription factor binding. Biological Process: adult heart development; heart morphogenesis; tongue development; neural crest cell development; thymus development; transcription, DNA-dependent; apoptosis; in utero embryonic development; negative regulation of transcription factor activity; positive regulation of transcription, DNA-dependent; heart development; mesenchymal cell proliferation; palate development; negative regulation of DNA binding; odontogenesis of dentine-containing teeth; peripheral nervous system neuron development; sympathetic nervous system development; suckling behavior; regulation of transcription, DNA-dependent; negative regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; embryonic digit morphogenesis; angiogenesis; heart looping

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095