Human Four and a half LIM domains protein 2, FHL2 ELISA Kit | MyBioSource MBS9335021 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Four and a half LIM domains protein 2, FHL2 ELISA Kit

catalog :

MBS9335021

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9335021

products type :

ELISA Kit

products full name :

Human Four and a half LIM domains protein 2, FHL2 ELISA Kit

products short name :

[four and a half LIM domains 2]

products name syn :

[Human Four and a half LIM domains protein 2 (FHL2) ELISA kit; AAG11; DRAL; SLIM3; OTTHUMP00000203164; OTTHUMP00000203168; OTTHUMP00000203169; aging-associated gene 11; down-regulated in rhabdomyosarcoma LIM protein; four and a half LIM-domain protein 2; four and a half LIM domains 2]

other names :

[four and a half LIM domains protein 2; Four and a half LIM domains protein 2; four and a half LIM domains protein 2; LIM domain protein DRAL; aging-associated gene 11; skeletal muscle LIM-protein 3; down-regulated in rhabdomyosarcoma LIM protein; four and a half LIM domains 2; LIM domain protein DRAL; Skeletal muscle LIM-protein 3; SLIM-3]

products gene name :

[FHL2]

other gene names :

[FHL2; FHL2; DRAL; AAG11; FHL-2; SLIM3; SLIM-3; DRAL; SLIM3; FHL-2; SLIM-3]

uniprot entry name :

FHL2_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of FHL2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

87159836

ncbi acc num :

NP_001034581.1

ncbi gb acc num :

NM_001039492.2

uniprot acc num :

Q14192

ncbi mol weight :

32,193 Da

ncbi pathways :

Androgen Receptor Signaling Pathway (198806); Coregulation Of Androgen Receptor Activity Pathway (138085); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Osteoclast Differentiation Pathway (193147); Osteoclast Differentiation Pathway (193096); PPARA Activates Gene Expression Pathway (530749); RANKL/RANK Signaling Pathway (672447); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544)

ncbi summary :

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2011]

uniprot summary :

FHL2: May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 2q12.2. Cellular Component: nucleoplasm; focal adhesion; M band; Z disc; nucleus; actin cytoskeleton. Molecular Function: identical protein binding; protein binding; androgen receptor binding; zinc ion binding; transcription coactivator activity; transcription factor binding. Biological Process: osteoblast differentiation; transcription, DNA-dependent; atrial cardiac muscle cell development; positive regulation of transcription, DNA-dependent; androgen receptor signaling pathway; ventricular cardiac muscle cell development; response to hormone stimulus; negative regulation of transcription from RNA polymerase II promoter; cellular lipid metabolic process; negative regulation of apoptosis

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage