catalog number :
MBS9334832
products type :
ELISA Kit
products full name :
Human Leucyl-tRNA synthetase, cytoplasmic, LARS ELISA Kit
products short name :
[leucyl-tRNA synthetase]
products name syn :
[Human Leucyl-tRNA synthetase; cytoplasmic (LARS) ELISA kit; FLJ10595; FLJ21788; HSPC192; KIAA1352; LARS1; LEURS; LEUS; LRS; PIG44; RNTLS; hr025Cl; cytoplasmic leucyl-tRNA synthetase; cytosolic leucyl-tRNA synthetase; leucine tRNA ligase 1; cytoplasmic; leucine; leucyl-tRNA synthetase]
other names :
[leucine--tRNA ligase, cytoplasmic; Leucine--tRNA ligase, cytoplasmic; leucine--tRNA ligase, cytoplasmic; leucine translase; leucine-tRNA ligase; proliferation-inducing gene 44; cytosolic leucyl-tRNA synthetase; cytoplasmic leucyl-tRNA synthetase; leucine tRNA ligase 1, cytoplasmic; leucyl-tRNA synthetase, cytoplasmic; leucyl-tRNA synthetase; Leucyl-tRNA synthetase; LeuRS]
products gene name :
[LARS]
other gene names :
[LARS; LARS; LRS; LEUS; LFIS; LARS1; LEURS; PIG44; RNTLS; HSPC192; hr025Cl; KIAA1352; LeuRS]
uniprot entry name :
SYLC_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LARS (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_064502.9
ncbi gb acc num :
NM_020117.9
ncbi mol weight :
134,466 Da
ncbi pathways :
Aminoacyl-tRNA Biosynthesis Pathway (83030); Aminoacyl-tRNA Biosynthesis Pathway (424); Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway (413439); Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway (468360); Cytosolic TRNA Aminoacylation Pathway (105981); Gene Expression Pathway (105937); TRNA Aminoacylation Pathway (105980)
ncbi summary :
This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. Alternatively spliced transcript variants of this gene have been found; however, their full-length nature is not known. [provided by RefSeq, Jul 2008]
uniprot summary :
LARS: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs. Belongs to the class-I aminoacyl-tRNA synthetase family. Protein type: Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; EC 6.1.1.4; Translation; Ligase. Chromosomal Location of Human Ortholog: 5q32. Cellular Component: cytoplasm; nucleus; cytosol. Molecular Function: methionine-tRNA ligase activity; leucine-tRNA ligase activity; protein binding; ATP binding. Biological Process: leucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation; regulation of translational fidelity; methionyl-tRNA aminoacylation; gene expression. Disease: Infantile Liver Failure Syndrome 1
size4 :
10x96-Strip-Wells