catalog number :
MBS9334779
products type :
ELISA Kit
products full name :
Mouse UDP-glucose 4-epimerase, GALE ELISA Kit
products short name :
[UDP-galactose-4-epimerase]
products name syn :
[Mouse UDP-glucose 4-epimerase (GALE) ELISA kit; RP5-886K2.6; FLJ95174; FLJ97302; SDR1E1; UDP galactose-4 -epimerase; UDP-glucose 4-epimerase; galactose-4-epimerase; UDP-; galactowaldenase; short chain dehydrogenase/reductase family 1E; member 1; UDP-galactose-4-epimerase]
other names :
[UDP-glucose 4-epimerase; UDP-glucose 4-epimerase; UDP-glucose 4-epimerase; galactowaldenase; UDP-galactose 4-epimerase; galactose-4-epimerase, UDP; Galactowaldenase; UDP-galactose 4-epimerase]
products gene name :
[GALE]
other gene names :
[Gale; Gale; AI323962; 2310002A12Rik]
uniprot entry name :
GALE_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GALE (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_848476.1
ncbi gb acc num :
NM_178389.3
ncbi mol weight :
38,225 Da
ncbi pathways :
Amino Sugar And Nucleotide Sugar Metabolism Pathway (83178); Amino Sugar And Nucleotide Sugar Metabolism Pathway (350); Disease Pathway (970606); Galactose Catabolism Pathway (970708); Galactose Degradation, Leloir Pathway, Galactose = Alpha-D-glucose-1P (961268); Galactose Degradation, Leloir Pathway, Galactose = Alpha-D-glucose-1P (966887); Galactose Metabolism Pathway (83131); Galactose Metabolism Pathway (292); Glycogen Storage Diseases Pathway (970607); Leloir Pathway (542861)
uniprot summary :
GALE: Catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. Defects in GALE are the cause of epimerase-deficiency galactosemia (EDG); also known as galactosemia type 3. Clinical features include early-onset cataracts, liver damage, deafness and mental retardation. There are two clinically distinct forms of EDG. (1) A benign, or peripheral form with no detectable GALE activity in red blood cells and characterized by mild symptoms. Some patients may suffer no symptoms beyond raised levels of galactose-1-phosphate in the blood. (2) A much rarer generalized form with undetectable levels of GALE activity in all tissues and resulting in severe features such as restricted growth and mental development. Belongs to the sugar epimerase family. Protein type: Carbohydrate Metabolism - galactose; Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 5.1.3.7; EC 5.1.3.2; Isomerase. Molecular Function: UDP-N-acetylglucosamine 4-epimerase activity; protein homodimerization activity; racemase and epimerase activity, acting on carbohydrates and derivatives; isomerase activity; UDP-glucose 4-epimerase activity; coenzyme binding; catalytic activity. Biological Process: galactose catabolic process; carbohydrate metabolic process; galactose metabolic process
size4 :
10x96-Strip-Wells