product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human DNA repair protein XRCC1, XRCC1 ELISA Kit
catalog :
MBS9334238
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9334238
products type :
ELISA Kit
products full name :
Human DNA repair protein XRCC1, XRCC1 ELISA Kit
products short name :
[X-ray repair complementing defective repair in Chinese hamster cells 1]
products name syn :
[Human DNA repair protein XRCC1 (XRCC1) ELISA kit; RCC; DNA repair protein XRCC1; X-ray repair cross complementing protein 1; X-ray-repair; complementing defective; repair in Chinese hamster; X-ray repair complementing defective repair in Chinese hamster cells 1]
other names :
[DNA repair protein XRCC1; DNA repair protein XRCC1; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1; X-ray repair complementing defective repair in Chinese hamster cells 1; X-ray repair cross-complementing protein 1]
products gene name :
[XRCC1]
other gene names :
[XRCC1; XRCC1; RCC]
uniprot entry name :
XRCC1_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml
other info2 :
Intra-assay Precision: Intra-assay CV(%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of XRCC1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
190684675
ncbi acc num :
NP_006288.2
ncbi gb acc num :
NM_006297.2
uniprot acc num :
P18887
ncbi mol weight :
69,477 Da
ncbi pathways :
BER Complex Pathway (413429); BER Complex Pathway (468377); Base Excision Repair Pathway (105838); Base Excision Repair Pathway (83043); Base Excision Repair Pathway (451); DNA Repair Pathway (105837); E2F Transcription Factor Network Pathway (137934); FOXM1 Transcription Factor Network Pathway (137935); Resolution Of AP Sites Via The Single-nucleotide Replacement Pathway (105847); Resolution Of Abasic Sites (AP Sites) Pathway (105846)
ncbi summary :
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
uniprot summary :
XRCC1: Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Homodimer. Interacts with polynucleotide kinase (PNK), DNA polymerase-beta (POLB) and DNA ligase III (LIG3). Interacts with APTX and APLF. Interacts with APEX1; the interaction is induced by SIRT1 and increases with the acetylated form of APEX1. Protein type: DNA repair, damage. Chromosomal Location of Human Ortholog: 19q13.2. Cellular Component: nucleoplasm; nucleus. Molecular Function: protein binding; enzyme binding; damaged DNA binding. Biological Process: single strand break repair; base-excision repair; DNA repair
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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