Mouse Pre-B-cell leukemia transcription factor 1, PBX1 ELISA Kit | MyBioSource MBS9334170 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Pre-B-cell leukemia transcription factor 1, PBX1 ELISA Kit

catalog :

MBS9334170

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9334170

products type :

ELISA Kit

products full name :

Mouse Pre-B-cell leukemia transcription factor 1, PBX1 ELISA Kit

products short name :

[pre-B-cell leukemia homeobox 1]

products name syn :

[Mouse Pre-B-cell leukemia transcription factor 1 (PBX1) ELISA kit; DKFZp686B09108; MGC126627; Pre-B cell leukemia transcription factor-1; pre-B-cell leukemia transcription factor 1; pre-B-cell leukemia homeobox 1]

other names :

[pre-B-cell leukemia transcription factor 1 isoform b; Pre-B-cell leukemia transcription factor 1; pre-B-cell leukemia transcription factor 1; homeobox protein PBX1; pre B cell leukemia homeobox 1; Homeobox protein PBX1]

products gene name :

[PBX1]

other gene names :

[Pbx1; Pbx1; Pbx-1; 2310056B04Rik; D230003C07Rik; Pbx-1]

uniprot entry name :

PBX1_MOUSE

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 62.5 pg/ml - 2000 pg/ml. Sensitivity: 10 pg/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PBX1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

614458205

ncbi acc num :

NP_001278437.1

ncbi gb acc num :

NM_001291508.1

uniprot acc num :

P41778

ncbi mol weight :

46,626 Da

ncbi pathways :

Developmental Biology Pathway (970813); Transcriptional Misregulation In Cancer Pathway (523020); Transcriptional Misregulation In Cancer Pathway (522987); Transcriptional Regulation Of Pluripotent Stem Cells Pathway (1000799)

ncbi summary :

This gene encodes a homeobox protein that belongs to the three-amino-acid loop extension/Pre-B cell leukemia transcription factor (TALE/PBX) family of proteins. The encoded protein is involved in several biological processes during embryogenesis including steroidogenesis, sexual development and the maintenance of hematopoietic stem cells. This protein functions in the development of several organ systems and plays a role in skeletal patterning and programming. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

uniprot summary :

PBX1: Binds the sequence 5 -ATCAATCAA-3 . Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1;19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Forms a heterodimer with MEIS1 which binds DNA including a cAMP-responsive sequence in CYP17. Also forms heterotrimers with MEIS1 and a number of HOX proteins including HOXA9, HOXD4, HOXD9 and HOXD10. Interacts with PBXIP1. Expressed in all tissues except in cells of the B and T lineage. Belongs to the TALE/PBX homeobox family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; Oncoprotein; DNA-binding; Transcription factor. Cellular Component: nucleoplasm; transcription factor complex; cytoplasm; nucleus. Molecular Function: protein binding; DNA binding; sequence-specific DNA binding; protein heterodimerization activity; transcription factor activity; transcription factor binding. Biological Process: transcription from RNA polymerase II promoter; embryonic skeletal development; multicellular organismal development; anterior/posterior pattern formation; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; cell differentiation; proximal/distal pattern formation; embryonic limb morphogenesis; spleen development; transcription, DNA-dependent; thymus development; embryonic hemopoiesis; adrenal gland development; negative regulation of transcription factor activity; regulation of cell proliferation; negative regulation of neuron differentiation; organ morphogenesis; ureteric bud branching; embryonic organ development; positive regulation of transcription from RNA polymerase II promoter; regulation of ossification; sex differentiation; steroid biosynthetic process; urogenital system development

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095