Human C-Jun-amino-terminal kinase-interacting protein 4, SPAG9 ELISA Kit | MyBioSource MBS9334122 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human C-Jun-amino-terminal kinase-interacting protein 4, SPAG9 ELISA Kit

catalog :

MBS9334122

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9334122

products type :

ELISA Kit

products full name :

Human C-Jun-amino-terminal kinase-interacting protein 4, SPAG9 ELISA Kit

products short name :

sperm associated antigen 9

products name syn :

Human C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9) ELISA kit; CT89; FLJ13450; FLJ14006; FLJ26141; FLJ34602; HLC4; JLP; KIAA0516; MGC117291; MGC14967; MGC74461; PHET; PIG6; HLC-4 protein; JNK interacting protein; JNK-associated leucine-zipper protein; JNK/SAPK-ass; sperm associated antigen 9

other names :

C-Jun-amino-terminal kinase-interacting protein 4 isoform 2; C-Jun-amino-terminal kinase-interacting protein 4; C-Jun-amino-terminal kinase-interacting protein 4; sunday driver 1; Max-binding protein; sperm surface protein; lung cancer oncogene 4; JNK interacting protein; cancer/testis antigen 89; JNK/SAPK-associated protein; proliferation-inducing gene 6; protein highly expressed in testis; human lung cancer oncogene 6 protein; sperm associated antigen 9 variant 5; mitogen-activated protein kinase 8-interacting protein 4; c-Jun NH2-terminal kinase-associated leucine zipper protein; sperm associated antigen 9; Cancer/testis antigen 89; CT89; Human lung cancer oncogene 6 protein; HLC-6; JNK-associated leucine-zipper protein; JLP; Mitogen-activated protein kinase 8-interacting protein 4; Proliferation-inducing protein 6; Protein highly expressed in testis; PHET; Sperm surface protein; Sperm-associated antigen 9; Sperm-specific protein; Sunday driver 1

products gene name :

SPAG9

other gene names :

SPAG9; SPAG9; JLP; CT89; HLC4; HLC6; JIP4; PHET; PIG6; HLC-6; JIP-4; HSS; KIAA0516; MAPK8IP4; SYD1; HLC6; JIP-4; JNK-interacting protein 4; CT89; HLC-6; JLP; PHET

uniprot entry name :

JIP4_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SPAG9 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

194578921

ncbi acc num :

NP_001123999.1

ncbi gb acc num :

NM_001130527.2

uniprot acc num :

O60271

ncbi mol weight :

146,205 Da

ncbi pathways :

Arf6 Trafficking Events Pathway (137954); CDO In Myogenesis Pathway (160998); Developmental Biology Pathway (477129); Myogenesis Pathway (160997)

ncbi summary :

This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]

uniprot summary :

JIP4: The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Isoform 5 may play a role in spermatozoa-egg- interaction. Homooligomer. Interacts with MAX, MAPK8, MAPK9, MAPK10, MAPK14, MAP3K3, MYC, KNS2 and MAP2K4. Interaction with KNS2 is important in the formation of ternary complex with MAPK8. Interacts with NFKB1. Isoform 3 is increased in systemic sclerosis fibroblasts. Isoform 5 is expressed only in testis on the round spermatids of stage I, II and II. Isoform 5 is absent in spermatogonia and spermatocyte. Isoform 3 is expressed in testis. Isoform 4 is expressed in testis and in acute myeloid leukemia (AML) patients. Belongs to the JIP scaffold family. 6 isoforms of the human protein are produced by alternative splicing. Protein type: Adaptor/scaffold; Cancer Testis Antigen (CTA). Chromosomal Location of Human Ortholog: 17q21.33. Cellular Component: perinuclear region of cytoplasm; cytoplasm; acrosome; integral to membrane; cytosol. Molecular Function: JUN kinase binding; protein binding; MAP-kinase scaffold activity; mitogen-activated protein kinase p38 binding; receptor signaling complex scaffold activity; kinesin binding. Biological Process: muscle cell differentiation; positive regulation of muscle cell differentiation; striated muscle cell differentiation; spermatogenesis; positive regulation of neuron differentiation; retrograde transport, endosome to Golgi; activation of JNK activity; protein homooligomerization; positive regulation of cell migration

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage