catalog number :
MBS9333772
products type :
ELISA Kit
products full name :
Mouse Forkhead box protein O4, FOXO4 ELISA Kit
products short name :
[forkhead box O4]
products name syn :
[Mouse Forkhead box protein O4 (FOXO4) ELISA kit; AFX; AFX1; MGC120490; MLLT7; fork head domain transcription factor AFX1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog) ; translocated to; 7; myeloid/lymphoid or mixed-lineage leukemia; forkhead box O4]
other names :
[forkhead box protein O4; Forkhead box protein O4; forkhead box protein O4; forkhead protein; fork head domain transcription factor AFX1; myeloid/lymphoid or mixed lineage-leukemia translocation to 7 homolog; forkhead box O4; Afxh; Fork head domain transcription factor AFX1]
products gene name :
[FOXO4]
other gene names :
[Foxo4; Foxo4; afx; Afxh; Mllt7; Afx; Afx1; Fkhr3; Mllt7]
uniprot entry name :
FOXO4_MOUSE
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Rat Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 62.5pg/ml-2000pg/ml. Sensitivity: 10pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of FOXO4 (hereafter termed "analyte") in undiluted original Rat serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_061259.1
ncbi gb acc num :
NM_018789.2
ncbi mol weight :
53,649 Da
ncbi pathways :
AKT Phosphorylates Targets In The Nucleus Pathway (1000608); Adaptive Immune System Pathway (971210); Constitutive PI3K/AKT Signaling In Cancer Pathway (1000676); DAP12 Interactions Pathway (971203); DAP12 Signaling Pathway (971214); Disease Pathway (970606); Downstream Signal Transduction Pathway (971469); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (1001193); Downstream Signaling Of Activated FGFR Pathway (971322); Fc Epsilon Receptor (FCERI) Signaling Pathway (970714)
uniprot summary :
FOXO4: transcription factor AFX1 containing 1 fork-head domain. May play a role in the insulin signaling pathway. Involved in acute leukemias by a chromosomal translocation t(X;11)(q13;q23) that involves MLLT7 and MLL/HRX. The result is a rogue activator protein. Two splice-variant isoforms have been described. Protein type: Oncoprotein; Transcription factor; DNA-binding. Cellular Component: nucleoplasm; cytoplasm; nucleus; cytosol. Molecular Function: protein binding; enzyme binding; DNA binding; sequence-specific DNA binding; transcription factor binding; transcription factor activity. Biological Process: transcription from RNA polymerase II promoter; muscle development; transcription, DNA-dependent; multicellular organismal development; positive regulation of transcription, DNA-dependent; negative regulation of smooth muscle cell differentiation; stem cell differentiation; cell cycle; regulation of transcription from RNA polymerase II promoter; negative regulation of cell proliferation; negative regulation of angiogenesis; regulation of transcription, DNA-dependent; mitotic cell cycle G2/M transition DNA damage checkpoint; insulin receptor signaling pathway; cell differentiation; cell cycle arrest
size4 :
10x96-Strip-Wells