Mouse Mitofusin-2, MFN2 ELISA Kit | MyBioSource MBS9333527 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Mitofusin-2, MFN2 ELISA Kit

catalog :

MBS9333527

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9333527

products type :

ELISA Kit

products full name :

Mouse Mitofusin-2, MFN2 ELISA Kit

products short name :

[mitofusin 2]

products name syn :

[Mouse Mitofusin-2 (MFN2) ELISA kit; RP5-1077B9.3; CMT2A; CMT2A2; CPRP1; HSG; KIAA0214; MARF; hyperplasia suppressor; mitochondrial assembly regulatory factor; mitofusin-2; transmembrane GTPase MFN2; mitofusin 2]

other names :

[mitofusin-2; Mitofusin-2; mitofusin-2; HSG protein; transmembrane GTPase MFN2; hypertension related protein 1; hypertension-related protein 1; mitochondrial assembly regulatory factor; mitofusin 2; Hypertension-related protein 1; Mitochondrial assembly regulatory factor; HSG protein; Transmembrane GTPase MFN2]

products gene name :

[MFN2]

other gene names :

[Mfn2; Mfn2; Fzo; D630023P19Rik; Kiaa0214; Marf; HSG protein]

uniprot entry name :

MFN2_MOUSE

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MFN2 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

553727138

ncbi acc num :

NP_001272849.1

ncbi gb acc num :

NM_001285920.1

uniprot acc num :

Q80U63

ncbi mol weight :

86,188 Da

ncbi pathways :

Factors Involved In Megakaryocyte Development And Platelet Production Pathway (1001326); Hemostasis Pathway (1001295)

uniprot summary :

MFN2: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Defects in MFN2 are the cause of Charcot-Marie-Tooth disease type 2A2 (CMT2A2). CMT2A2 is a form of Charcot-Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathy or CMT1, and primary peripheral axonal neuropathy or CMT2. Neuropathies of the CMT2 group are characterized by signs of axonal regeneration in the absence of obvious myelin alterations, normal or slightly reduced nerve conduction velocities, and progressive distal muscle weakness and atrophy. Defects in MFN2 are the cause of Charcot-Marie-Tooth disease type 6 (CMT6); also referred to as autosomal dominant hereditary motor and sensory neuropathy VI (HMSN6). CMT6 is an autosomal dominant form of axonal CMT associated with optic atrophy. Belongs to the mitofusin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cytoskeletal; Mitochondrial; Hydrolase; EC 3.6.5.-; Cell cycle regulation; Membrane protein, integral; Membrane protein, multi-pass. Cellular Component: microtubule cytoskeleton; mitochondrial outer membrane; membrane; mitochondrion; integral to membrane; cytosol; intrinsic to mitochondrial outer membrane. Molecular Function: GTPase activity; protein binding; GTPase binding; GTP binding; hydrolase activity; ubiquitin protein ligase binding; nucleotide binding. Biological Process: camera-type eye morphogenesis; mitochondrial fusion; negative regulation of smooth muscle cell proliferation; apoptosis; mitochondrial membrane organization and biogenesis; multicellular organismal development; autophagy; negative regulation of Ras protein signal transduction; blastocyst formation; mitochondrion localization; protein targeting to mitochondrion; response to unfolded protein

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095