Human Sodium-dependent phosphate transport protein 2B, SLC34A2 ELISA Kit | MyBioSource MBS9333475 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Sodium-dependent phosphate transport protein 2B, SLC34A2 ELISA Kit

catalog :

MBS9333475

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9333475

products type :

ELISA Kit

products full name :

Human Sodium-dependent phosphate transport protein 2B, SLC34A2 ELISA Kit

products short name :

[solute carrier family 34 (sodium phosphate) , member 2]

products name syn :

[Human Sodium-dependent phosphate transport protein 2B (SLC34A2) ELISA kit; FLJ90534; NAPI-3B; NAPI-IIb; NPTIIb; sodium-phosphate transporter; type II sodium-dependent phosphate transporter 3b; solute carrier family 34 (sodium phosphate); member 2]

other names :

[sodium-dependent phosphate transport protein 2B isoform b; Sodium-dependent phosphate transport protein 2B; sodium-dependent phosphate transport protein 2B; sodium/phosphate cotransporter 2B; type II sodium-dependent phosphate transporter 3b; solute carrier family 34 (sodium phosphate), member 2; solute carrier family 34 (type II sodium/phosphate contransporter), member 2; Na(+)-dependent phosphate cotransporter 2B; NaPi3b; Sodium/phosphate cotransporter 2B; Na(+)/Pi cotransporter 2B; NaPi-2b; Solute carrier family 34 member 2]

products gene name :

[SLC34A2]

other gene names :

[SLC34A2; SLC34A2; NPTIIb; NAPI-3B; NAPI-IIb; Sodium-phosphate transport protein 2B; Na(+)/Pi cotransporter 2B; NaPi-2b]

uniprot entry name :

NPT2B_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 62.5 pg/ml - 2000 pg/ml. Sensitivity: 10 pg/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SLC34A2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

295789158

ncbi acc num :

NP_001171469.1

ncbi gb acc num :

NM_001177998.1

uniprot acc num :

O95436

ncbi mol weight :

75,759 Da

ncbi pathways :

Mineral Absorption Pathway (212237); Mineral Absorption Pathway (212220); SLC-mediated Transmembrane Transport Pathway (119558); Sodium-coupled Phosphate Cotransporters Pathway (119565); Transmembrane Transport Of Small Molecules Pathway (106572); Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway (119559); Type II Na+/Pi Cotransporters Pathway (119566)

ncbi summary :

The protein encoded by this gene is a pH-sensitive sodium-dependent phosphate transporter. Phosphate uptake is increased at lower pH. Defects in this gene are a cause of pulmonary alveolar microlithiasis. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, May 2010]

uniprot summary :

SLC34A2: May be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs alveoli. Defects in SLC34A2 are a cause of pulmonary alveolar microlithiasis (PALM). Pulmonary alveolar microlithiasis is a rare disease characterized by the deposition of calcium phosphate microliths throughout the lungs. Most patients are asymptomatic for several years or even for decades and generally, the diagnosis is incidental to clinical investigations unrelated to the disease. Cases with early onset or rapid progression are rare. A sandstorm-appearing chest roentgenogram is a typical diagnostic finding. The onset of this potentially lethal disease varies from the neonatal period to old age and the disease follows a long-term, progressive course, resulting in a slow deterioration of lung functions. Pulmonary alveolar microlithiasis is a recessive monogenic disease with full penetrance. A chromosomal aberration involving SLC34A2 is found in a non-small cell lung cancer cell line. Results in the formation of a SLC34A2-ROS1 chimeric protein that retains a constitutive kinase activity. Belongs to the SLC34A transporter family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral; Transporter. Chromosomal Location of Human Ortholog: 4p15.2. Cellular Component: brush border membrane; integral to plasma membrane; microvillus membrane; apical plasma membrane; plasma membrane; integral to membrane; vesicle. Molecular Function: protein domain specific binding; sodium ion binding; phosphate binding; sodium:phosphate symporter activity; sodium-dependent phosphate transmembrane transporter activity. Biological Process: cellular phosphate ion homeostasis; phosphate transport; response to estrogen stimulus; in utero embryonic development; ion transport; transmembrane transport; response to estradiol stimulus; response to fructose stimulus; aging. Disease: Pulmonary Alveolar Microlithiasis; Testicular Microlithiasis

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage