product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Ras-specific guanine nucleotide-releasing factor 2, RASGRF2 ELISA Kit
catalog :
MBS9333238
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9333238
products type :
ELISA Kit
products full name :
Human Ras-specific guanine nucleotide-releasing factor 2, RASGRF2 ELISA Kit
products short name :
[Ras protein-specific guanine nucleotide-releasing factor 2]
products name syn :
[Human Ras-specific guanine nucleotide-releasing factor 2 (RASGRF2) ELISA kit; DKFZp781H1715; GRF2; RAS-GRF2; ; Ras protein-specific guanine nucleotide-releasing factor 2]
other names :
[ras-specific guanine nucleotide-releasing factor 2; Ras-specific guanine nucleotide-releasing factor 2; ras-specific guanine nucleotide-releasing factor 2; ras guanine nucleotide exchange factor 2; Ras protein-specific guanine nucleotide-releasing factor 2; Ras guanine nucleotide exchange factor 2]
products gene name :
[RASGRF2]
other gene names :
[RASGRF2; RASGRF2; GRF2; RAS-GRF2; GRF2; Ras-GRF2]
uniprot entry name :
RGRF2_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RASGRF2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
38505170
ncbi acc num :
NP_008840.1
ncbi gb acc num :
NM_006909.2
uniprot acc num :
O14827
ncbi mol weight :
140,764 Da
ncbi pathways :
Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway (161033); CREB Phosphorylation Through The Activation Of Ras Pathway (161036); Cell Death Signalling Via NRAGE, NRIF And NADE Pathway (106443); G Alpha (12/13) Signalling Events Pathway (106041); GPCR Downstream Signaling Pathway (119548); MAPK Signaling Pathway (198779); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); NRAGE Signals Death Through JNK Pathway (106444); Neuronal System Pathway (106513)
ncbi summary :
RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways. [provided by RefSeq, Oct 2011]
uniprot summary :
RASGRF2: Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation. Protein type: GEFs; GEFs, Ras. Chromosomal Location of Human Ortholog: 5q13. Cellular Component: endoplasmic reticulum membrane; plasma membrane; cytosol. Molecular Function: calmodulin binding; Rho guanyl-nucleotide exchange factor activity. Biological Process: synaptic transmission; regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; small GTPase mediated signal transduction
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

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