catalog number :
MBS9333224
products type :
ELISA Kit
products full name :
Bovine Nucleotide-binding oligomerization domain-containing protein 2, NOD2 ELISA Kit
products short name :
nucleotide-binding oligomerization domain containing 2
products name syn :
Bovine Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) ELISA kit; ACUG; BLAU; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2B; PSORAS1; NLR family; CARD domain containing 2; NOD-like receptor C2; caspase recruitment domain family; member 15; caspase recruitment domain protei; nucleotide-binding oligomerization domain containing 2
other names :
nucleotide-binding oligomerization domain-containing protein 2; Nucleotide-binding oligomerization domain-containing protein 2; nucleotide-binding oligomerization domain-containing protein 2; caspase recruitment domain 15 protein; caspase recruitment domain-containing protein 15; nucleotide-binding oligomerization domain containing 2<; Caspase recruitment domain-containing protein 15
products gene name :
NOD2
other gene names :
NOD2; NOD2; CARD15; CARD15
uniprot entry name :
NOD2_BOVIN
ncbi acc num :
NP_001002889.1
ncbi gb acc num :
NM_001002889.1
ncbi mol weight :
112,800 Da
ncbi pathways :
Activated TLR4 Signalling Pathway 581575!!Cytokine Signaling In Immune System Pathway 581601!!Immune System Pathway 581534!!Innate Immune System Pathway 581553!!Interleukin-1 Signaling Pathway 581603!!MyD88 Cascade Initiated On Plasma Membrane Pathway 581556!!MyD88 Dependent Cascade Initiated On Endosome Pathway 581570!!MyD88-independent Cascade Initiated On Plasma Membrane Pathway 581577!!MyD88:Mal Cascade Initiated On Plasma Membrane Pathway 581576!!NFkB And MAP Kinases Activation Mediated By TLR4 Signaling Repertoire Pathway 581579
uniprot summary :
Function: Recognizes muramyl dipeptide (MDP) constituents of bacterial peptidoglycans and plays a key role in gastrointestinal immunity: upon stimulation, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling, leading to activate the transcription of hundreds of genes involved in immune response