catalog number :
MBS9333054
products type :
ELISA Kit
products full name :
Human Histone-lysine N-methyltransferase SETDB2, SETDB2 ELISA Kit
products short name :
[SET domain, bifurcated 2]
products name syn :
[Human Histone-lysine N-methyltransferase SETDB2 (SETDB2) ELISA kit; C13orf4; CLLD8; CLLL8; DKFZp586I0123; DKFZp761J1217; KMT1F; chronic lymphocytic leukemia deletion region 8; lysine N-methyltransferase 1F; SET domain; bifurcated 2]
other names :
[histone-lysine N-methyltransferase SETDB2; Histone-lysine N-methyltransferase SETDB2; histone-lysine N-methyltransferase SETDB2; Setdb2-Phf11-1-Phf11-2 fusion; SET domain, bifurcated 2; SET domain bifurcated 2]
products gene name :
[SETDB2]
other gene names :
[Setdb2; Setdb2; Clld8; Gm293; KMT1F; Gm293]
uniprot entry name :
SETB2_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of SESN1 (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001074493.1
ncbi gb acc num :
NM_001081024.1
ncbi mol weight :
80,636 Da
ncbi pathways :
Lysine Degradation Pathway (83156); Lysine Degradation Pathway (320)
uniprot summary :
SETDB2: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates Lys-9 of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis. Belongs to the histone-lysine methyltransferase family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Methyltransferase, protein lysine; EC 2.1.1.43; Methyltransferase; Amino Acid Metabolism - lysine degradation. Cellular Component: chromosome; nucleus. Molecular Function: transferase activity; methyltransferase activity; DNA binding; zinc ion binding; metal ion binding; histone lysine N-methyltransferase activity (H3-K9 specific); histone-lysine N-methyltransferase activity. Biological Process: methylation; mitosis; cell division; multicellular organismal development; chromatin modification; cell cycle; chromosome segregation; histone H3-K9 methylation; peptidyl-lysine methylation
size4 :
10x96-Strip-Wells