Human Group 3 secretory phospholipase A2, PLA2G3 ELISA Kit | MyBioSource MBS9333034 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Group 3 secretory phospholipase A2, PLA2G3 ELISA Kit

catalog :

MBS9333034

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9333034

products type :

ELISA Kit

products full name :

Human Group 3 secretory phospholipase A2, PLA2G3 ELISA Kit

products short name :

[phospholipase A2, group III]

products name syn :

[Human Group 3 secretory phospholipase A2 (PLA2G3) ELISA kit; GIII-SPLA2; SPLA2III; group III secreted phospholipase A2; phosphatidylcholine 2-acylhydrolase GIII; phospholipase A2; group III]

other names :

[group 3 secretory phospholipase A2; Group 3 secretory phospholipase A2; group 3 secretory phospholipase A2; group III secreted phospholipase A2; phosphatidylcholine 2-acylhydrolase 3; phosphatidylcholine 2-acylhydrolase GIII; phospholipase A2, group III; Group III secretory phospholipase A2; GIII sPLA2; sPLA2-III; Phosphatidylcholine 2-acylhydrolase 3]

products gene name :

[PLA2G3]

other gene names :

[PLA2G3; PLA2G3; SPLA2III; sPLA2-III; GIII-SPLA2; GIII sPLA2; sPLA2-III]

uniprot entry name :

PA2G3_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PLA2G3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

142976884

ncbi acc num :

NP_056530.2

ncbi gb acc num :

NM_015715.4

uniprot acc num :

Q9NZ20

ncbi mol weight :

57,167 Da

ncbi pathways :

Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (366); Ether Lipid Metabolism Pathway (82990); Ether Lipid Metabolism Pathway (365); Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); Fc Epsilon RI Signaling Pathway (83082); Fc Epsilon RI Signaling Pathway (493); Glutamatergic Synapse Pathway (213818); Glutamatergic Synapse Pathway (213811)

ncbi summary :

This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease. [provided by RefSeq, Apr 2014]

uniprot summary :

PLA2G3: PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Shows an 11-fold preference for phosphatidylglycerol over phosphatidylcholine (PC). Preferential cleavage: 1-palmitoyl-2-linoleoyl- phosphatidylethanolamine (PE) 1-palmitoyl-2-linoleoyl-PC 1- palmitoyl-2-arachidonoyl-PC 1-palmitoyl-2-arachidonoyl-PE. Plays a role in ciliogenesis. Belongs to the phospholipase A2 family. Protein type: Lipid Metabolism - linoleic acid; Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - arachidonic acid; Lipid Metabolism - ether lipid; EC 3.1.1.4; Phospholipase. Chromosomal Location of Human Ortholog: 22q12.2. Cellular Component: centriole; extracellular space; mast cell granule; plasma membrane; extracellular region. Molecular Function: calcium-dependent phospholipase A2 activity; calcium ion binding. Biological Process: acrosome formation; lipoxygenase pathway; phospholipid metabolic process; glycerophospholipid biosynthetic process; sperm axoneme assembly; mast cell degranulation; lipid catabolic process

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095