catalog number :
MBS9332622
products type :
ELISA Kit
products full name :
Human Kelch domain-containing protein 5, KLHDC5 ELISA Kit
products short name :
[kelch domain containing 5]
products name syn :
[Human Kelch domain-containing protein 5 (KLHDC5) ELISA kit; Ctb9; KIAA1340; MGC131714; ; kelch domain containing 5]
other names :
[kelch-like protein 42; Kelch-like protein 42; kelch-like protein 42; kelch domain containing 5; cullin-3-binding protein 9; kelch-like family, member 42; kelch domain-containing protein 5; kelch-like family member 42; Cullin-3-binding protein 9; Ctb9; Kelch domain-containing protein 5]
products gene name :
[KLHDC5]
other gene names :
[KLHL42; KLHL42; Ctb9; KLHDC5; KIAA1340; KLHDC5; Ctb9]
uniprot entry name :
KLH42_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of KLHDC5 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_065833.1
ncbi gb acc num :
NM_020782.1
ncbi mol weight :
56,868 Da
uniprot summary :
KLHDC5: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis. Up-regulated during mitosis. Component of the BCR(KLHL42) E3 ubiquitin ligase complex, at least composed of CUL3 and KLHL42. Interacts (via the BTB domain) with CUL3. Interacts (via the kelch domains) with KATNA1. Protein type: Unknown function. Chromosomal Location of Human Ortholog: 12p11.22. Cellular Component: cytoplasm; spindle. Molecular Function: protein binding; ubiquitin-protein ligase activity. Biological Process: mitosis; regulation of microtubule-based process; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; cell division
size4 :
10x96-Strip-Wells