ELISA/assay

Human Tyrosine-protein kinase transmembrane receptor ROR1, ROR1 ELISA Kit

MBS9332608

48-Strip-Wells

470 USD

ELISA Kit

Human Tyrosine-protein kinase transmembrane receptor ROR1, ROR1 ELISA Kit

[receptor tyrosine kinase-like orphan receptor 1]

[Human Tyrosine-protein kinase transmembrane receptor ROR1 (ROR1) ELISA kit; RP11-24J23.1; MGC99659; NTRKR1; dJ537F10.1; neurotrophic tyrosine kinase receptor-related 1; receptor tyrosine kinase-like orphan receptor 1]

[tyrosine-protein kinase transmembrane receptor ROR1 isoform 2; Tyrosine-protein kinase transmembrane receptor ROR1; tyrosine-protein kinase transmembrane receptor ROR1; neurotrophic tyrosine kinase, receptor-related 1; receptor tyrosine kinase-like orphan receptor 1; Neurotrophic tyrosine kinase, receptor-related 1]

[ROR1]

[ROR1; ROR1; NTRKR1; dJ537F10.1; NTRKR1]

ROR1_HUMAN

Human

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ROR1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

134152686

NP_001077061.1

NM_001083592.1

Q01973

104,283 Da

Nuclear Receptors Pathway (198848)

This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]

ROR1: Tyrosine-protein kinase receptor whose role is not yet clear. Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Protein kinase, tyrosine (receptor); Membrane protein, integral; Kinase, protein; EC 2.7.10.1; Protein kinase, TK; TK group; Ror family. Chromosomal Location of Human Ortholog: 1p31.3. Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane; receptor complex. Molecular Function: Wnt-protein binding; protein binding; transmembrane receptor protein tyrosine kinase activity; ATP binding. Biological Process: peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095