product summary
Loading...
company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Segment polarity protein dishevelled homolog DVL-2, DVL2 ELISA Kit
catalog :
MBS9332533
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9332533
products type :
ELISA Kit
products full name :
Human Segment polarity protein dishevelled homolog DVL-2, DVL2 ELISA Kit
products short name :
dishevelled, dsh homolog 2 (Drosophila)
products name syn :
Human Segment polarity protein dishevelled homolog DVL-2 (DVL2) ELISA kit; DSH homolog 2; dishevelled 2; dishevelled 2 (homologous to Drosophila dsh) ; segment polarity protein dishevelled homolog DVL-2; dishevelled; dsh homolog 2 (Drosophila)
other names :
segment polarity protein dishevelled homolog DVL-2; Segment polarity protein dishevelled homolog DVL-2; segment polarity protein dishevelled homolog DVL-2; dishevelled, dsh homolog 2; dishevelled 2 (homologous to Drosophila dsh); dishevelled segment polarity protein 2; DSH homolog 2
products gene name :
DVL2
other gene names :
DVL2; DVL2; Dishevelled-2
uniprot entry name :
DVL2_HUMAN
reactivity :
Human
storage stability :
Store all reagents at 2-8 degree C
ncbi gi num :
4758216
ncbi acc num :
NP_004413.1
ncbi gb acc num :
NM_004422.2
uniprot acc num :
O14641
ncbi mol weight :
78,948 Da
ncbi pathways :
Basal Cell Carcinoma Pathway (83113); Basal Cell Carcinoma Pathway (525); Canonical Wnt Signaling Pathway (138032); DNA Damage Response (only ATM Dependent) Pathway (198827); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); Melanogenesis Pathway (83092); Melanogenesis Pathway (504); Noncanonical Wnt Signaling Pathway (169354); Notch Signaling Pathway (83062)
ncbi summary :
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008]
uniprot summary :
DVL2: a protein in the WNT/planar cell polarity (PCP) signaling pathway. Dvl2-deficient mice indicate that Dvl2 is essential for normal cardiac morphogenesis, somite segmentation and neural tube closure. Transduces the Wnt signal by interacting with the cytoplasmic Axin complex. Dvl and Axin each contain a DIX domains, which mediate their dynamic polymerization. The Dvl-Axin interaction is essential for Wnt signaling. Interacts through its PDZ domain with the C-terminal regions of VANGL1 and VANGL2. Interacts with Dixin and Rac. There is functional redundancy between Dvl1 and Dvl2 in some phenotypes. Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold. Chromosomal Location of Human Ortholog: 17p13.1. Cellular Component: apical part of cell; cytoplasm; plasma membrane; cytoplasmic vesicle; clathrin-coated endocytic vesicle; nucleus; cytosol. Molecular Function: identical protein binding; protein domain specific binding; protein binding; protein self-association; frizzled binding. Biological Process: segment specification; transcription from RNA polymerase II promoter; positive regulation of JNK activity; Wnt receptor signaling pathway; convergent extension involved in neural plate elongation; Wnt receptor signaling pathway, planar cell polarity pathway; positive regulation of transcription, DNA-dependent; heart development; neural tube closure; positive regulation of transcription factor activity; positive regulation of protein amino acid phosphorylation; Wnt receptor signaling pathway through beta-catenin
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!