catalog number :
MBS9332336
products type :
ELISA Kit
products full name :
Human Sphingosine 1-phosphate receptor 2, S1PR2 ELISA Kit
products short name :
sphingosine-1-phosphate receptor 2
products name syn :
Human Sphingosine 1-phosphate receptor 2 (S1PR2) ELISA kit; AGR16; EDG-5; EDG5; Gpcr13; H218; LPB2; S1P2; S1P receptor EDG5; endothelial differentiation; sphingolipid G-protein-coupled receptor; 5; sphingosine 1-phosphate receptor 2; sphingosine-1-phosphate receptor 2
other names :
sphingosine 1-phosphate receptor 2; Sphingosine 1-phosphate receptor 2; sphingosine 1-phosphate receptor 2; S1P receptor 2; S1P receptor EDG5; S1P receptor Edg-5; sphingosine 1-phosphate receptor Edg-5; endothelial differentiation G-protein coupled receptor 5; endothelial differentiation, sphingolipid G-protein-coupled receptor, 5; sphingosine-1-phosphate receptor 2; Endothelial differentiation G-protein coupled receptor 5; Sphingosine 1-phosphate receptor Edg-5; S1P receptor Edg-5
products gene name :
S1PR2
other gene names :
S1PR2; S1PR2; EDG5; H218; LPB2; S1P2; AGR16; EDG-5; Gpcr13; EDG5; S1P receptor 2; S1P2; S1P receptor Edg-5
uniprot entry name :
S1PR2_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of S1PR2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_004221.3
ncbi gb acc num :
NM_004230.3
ncbi mol weight :
38,867 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Lysosphingolipid And LPA Receptors Pathway (106376); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); S1P2 Pathway (138059); S1P3 Pathway (138063); Signal Transduction Pathway (477114)
ncbi summary :
This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. This protein participates in sphingosine 1-phosphate-induced cell proliferation, survival, and transcriptional activation [provided by RefSeq, Jul 2008]
uniprot summary :
EDG5: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Belongs to the G-protein coupled receptor 1 family. Protein type: Lipid-binding; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Receptor, GPCR; GPCR, family 1; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19p13.2. Cellular Component: integral to membrane; plasma membrane. Molecular Function: G-protein coupled receptor activity; integrin binding; G-protein-coupled receptor binding; lipid binding. Biological Process: G-protein coupled receptor protein signaling pathway; activation of MAPK activity; positive regulation of cell proliferation