ELISA/assay

Mouse Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, ALDH4A1 ELISA Kit

MBS9332194

48-Strip-Wells

470 USD

ELISA Kit

Mouse Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, ALDH4A1 ELISA Kit

[aldehyde dehydrogenase 4 family, member A1]

[Mouse Delta-1-pyrroline-5-carboxylate dehydrogenase; mitochondrial (ALDH4A1) ELISA kit; RP11-128M10.1; ALDH4; DKFZp779M035; P5CD; P5CDh; P5C dehydrogenase; aldehyde dehydrogenase 4A1; mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase; aldehyde dehydrogenase 4 family; member A1]

[delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; P5C dehydrogenase; aldehyde dehydrogenase family 4 member A1; L-glutamate gamma-semialdehyde dehydrogenase; aldehyde dehydrogenase 4 family, member A1; Aldehyde dehydrogenase family 4 member A1; L-glutamate gamma-semialdehyde dehydrogenase]

[ALDH4A1]

[Aldh4a1; Aldh4a1; Ahd1; P5cd; Ahd-1; Aldh4; P5cdh; Ssdh1; P5cdhl; P5cdhs; Aldh5a1; E330022C09; A930035F14Rik; P5C dehydrogenase]

AL4A1_MOUSE

Mouse

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ALDH4A1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

225543103

NP_780647.3

NM_175438.4

Q8CHT0

61,841 Da

Alanine, Aspartate And Glutamate Metabolism Pathway (101155); Alanine, Aspartate And Glutamate Metabolism Pathway (100063); Arginine And Proline Metabolism Pathway (83157); Arginine And Proline Metabolism Pathway (323); Metabolism Pathway (574739); Metabolism Of Amino Acids And Derivatives Pathway (574861); Proline Catabolism Pathway (574867); Arginine Degradation I (arginase Pathway) (142816); Proline Degradation III Pathway (142988)

ALDH4A1: Irreversible conversion of delta-1-pyrroline-5- carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes. Defects in ALDH4A1 are the cause of hyperprolinemia type 2 (HP-2). HP-2 is characterized by the accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. The disorder may be causally related to neurologic manifestations, including seizures and mental retardation. Belongs to the aldehyde dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 1.2.1.88; Mitochondrial; Amino Acid Metabolism - arginine and proline; Oxidoreductase; Amino Acid Metabolism - alanine, aspartate and glutamate. Cellular Component: mitochondrion. Molecular Function: identical protein binding; aldehyde dehydrogenase (NAD) activity; oxidoreductase activity; 1-pyrroline-5-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. Biological Process: proline biosynthetic process; metabolic process; glutamate biosynthetic process; proline metabolic process

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095