ELISA/assay

Human Carnitine O-palmitoyltransferase 1, liver isoform, CPT1A/CPT1 ELISA Kit

MBS9332032

48-Strip-Wells

470 USD

ELISA Kit

Human Carnitine O-palmitoyltransferase 1, liver isoform, CPT1A/CPT1 ELISA Kit

[carnitine palmitoyltransferase 1A (liver)]

[Human Carnitine O-palmitoyltransferase 1; liver isoform (CPT1A/CPT1) ELISA kit; CPT1; CPT1-L; L-CPT1; carnitine palmitoyltransferase 1A liver; carnitine palmitoyltransferase I; liver; carnitine palmitoyltransferase 1A (liver)]

[carnitine O-palmitoyltransferase 1, liver isoform isoform 2; Carnitine O-palmitoyltransferase 1, liver isoform; carnitine O-palmitoyltransferase 1, liver isoform; CPT I; CPTI-L; carnitine palmitoyltransferase I, liver; carnitine O-palmitoyltransferase I, liver isoform; carnitine palmitoyltransferase 1A (liver); Carnitine O-palmitoyltransferase I, liver isoform; CPT I; CPTI-L; Carnitine palmitoyltransferase 1A]

[CPT1A]

[CPT1A; CPT1A; CPT1; CPT1-L; L-CPT1; CPT1; CPT1-L; CPT I; CPTI-L]

CPT1A_HUMAN

Human

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich. Detection Range: 1.56ng/ml-50ng/ml. Sensitivity: 0.1ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CPT1A (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

73623028

NP_001027017.1

NM_001031847.2

P50416

88,368 Da

AMPK Signaling Pathway (198868); Adipocytokine Signaling Pathway (83093); Adipocytokine Signaling Pathway (505); Circadian Clock Pathway (187173); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Fatty Acid Beta Oxidation Pathway (198865); Fatty Acid Metabolism Pathway (82935); Fatty Acid Metabolism Pathway (296); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Import Of Palmitoyl-CoA Into The Mitochondrial Matrix Pathway (106108)

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function: Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism. Catalytic activity: Palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.2 PublicationsManual assertion based on experiment in:Ref.11. Enzyme regulation: Inhibited by malonyl-CoA.1 PublicationManual assertion based on experiment in:Ref.13

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095