Human Anosmin-1, KAL1 ELISA Kit | MyBioSource MBS933196 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Anosmin-1, KAL1 ELISA Kit

catalog :

MBS933196

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS933196

products type :

ELISA Kit

products full name :

Human Anosmin-1, KAL1 ELISA Kit

products short name :

Kallmann syndrome 1 sequence

products name syn :

Human Anosmin-1 (KAL1) ELISA kit; ADMLX; HHA; KAL; KALIG-1; KMS; Kallmann syndrome 1 protein; Kallmann syndrome interval gene 1; Kallmann syndrome-1 sequence (anosmin-1) ; adhesion molecule-like X-linked; anosmin-1; Kallmann syndrome 1 sequence

other names :

anosmin-1; Anosmin-1; anosmin-1; kallmann syndrome protein; adhesion molecule-like X-linked; Kallmann syndrome interval gene 1; WAP four-disulfide core domain 19; Kallmann syndrome-1 sequence (anosmin-1); Kallmann syndrome 1 sequence; Adhesion molecule-like X-linked; Kallmann syndrome protein

products gene name :

KAL1

other gene names :

KAL1; KAL1; HH1; HHA; KAL; KMS; ADMLX; WFDC19; KALIG-1; ADMLX; KAL; KALIG1

uniprot entry name :

KALM_HUMAN

reactivity :

Human

sequence length :

680

specificity :

This assay has high sensitivity and excellent specificity for detection of Human KAL1. No significant cross-reactivity or interference between Human KAL1 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 125 pg/ml-8000 pg/ml. Sensitivity: 31.25 pg/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Cell Adhesion. Protein Biological Process 3: Cell adhesion

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for KAL1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any KAL1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for KAL1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of KAL1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

119395746

ncbi acc num :

NP_000207.2

ncbi gb acc num :

NM_000216.2

uniprot acc num :

P23352

ncbi mol weight :

76,112 Da

ncbi summary :

Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity. [provided by RefSeq, Jul 2008]

uniprot summary :

KAL1: Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex. Chemoattractant for fetal olfactory epithelial cells. Defects in KAL1 are the cause of Kallmann syndrome type 1 (KAL1); also known as hypogonadotropic hypogonadism and anosmia. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin- releasing hormone-synthesizing neurons. In some patients other developmental anomalies can be present, which include renal agenesis, cleft lip and/or palate, selective tooth agenesis, and bimanual synkinesis. In some cases anosmia may be absent or inconspicuous. Protein type: Motility/polarity/chemotaxis; Extracellular matrix. Chromosomal Location of Human Ortholog: Xp22.32. Cellular Component: extracellular space; proteinaceous extracellular matrix; plasma membrane. Molecular Function: heparin binding; serine-type endopeptidase inhibitor activity; protein binding; extracellular matrix structural constituent. Biological Process: axon guidance; chemotaxis; cell adhesion; cell motility. Disease: Hypogonadotropic Hypogonadism 1 With Or Without Anosmia

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage