catalog number :
MBS9331877
products type :
ELISA Kit
products full name :
Human Rho guanine nucleotide exchange factor 15, ARHGEF15 ELISA Kit
products short name :
[Rho guanine nucleotide exchange factor (GEF) 15]
products name syn :
[Human Rho guanine nucleotide exchange factor 15 (ARHGEF15) ELISA kit; ARGEF15; FLJ13791; KIAA0915; MGC44868; Vsm-RhoGEF; OTTHUMP00000135329; Rho guanine exchange factor (GEF) 15; Rho guanine exchange factor 15; Rho guanine nucleotide exchange factor (GEF) 15]
other names :
[rho guanine nucleotide exchange factor 15; Rho guanine nucleotide exchange factor 15; rho guanine nucleotide exchange factor 15; ephexin-5; Rho guanine nucleotide exchange factor (GEF) 15; Ephexin-5; E5; Vsm-RhoGEF]
products gene name :
[ARHGEF15]
other gene names :
[ARHGEF15; ARHGEF15; E5; ARGEF15; Ephexin5; Vsm-RhoGEF; KIAA0915; E5]
uniprot entry name :
ARHGF_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 62.5 pg/ml - 2000 pg/ml. Sensitivity: 10 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ARHGEF15 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_079290.1
ncbi gb acc num :
NM_025014.1
ncbi mol weight :
91,940 Da
ncbi pathways :
EPHA Forward Signaling Pathway (138041); Regulation Of RhoA Activity Pathway (138070)
ncbi summary :
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene. [provided by RefSeq, Aug 2010]
uniprot summary :
ephexin-5: Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2. Protein type: GEFs; GEFs, Rac/Rho. Chromosomal Location of Human Ortholog: 17p13.1. Cellular Component: cytoplasm; dendrite. Molecular Function: protein binding; Rho guanyl-nucleotide exchange factor activity; GTPase activator activity. Biological Process: regulation of catalytic activity; positive regulation of stress fiber formation
size4 :
10x96-Strip-Wells