product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human ER degradation-enhancing alpha-mannosidase-like 1, EDEM1 ELISA Kit
catalog :
MBS9331741
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9331741
products type :
ELISA Kit
products full name :
Human ER degradation-enhancing alpha-mannosidase-like 1, EDEM1 ELISA Kit
products short name :
ER degradation enhancer, mannosidase alpha-like 1
products name syn :
Human ER degradation-enhancing alpha-mannosidase-like 1 (EDEM1) ELISA kit; EDEM; FLJ51559; FLJ51560; KIAA0212; ER degradation enhancing alpha mannosidase-like; ER degradation enhancer; mannosidase alpha-like 1
other names :
ER degradation-enhancing alpha-mannosidase-like protein 1; ER degradation-enhancing alpha-mannosidase-like protein 1; ER degradation-enhancing alpha-mannosidase-like protein 1; ER degradation-enhancing alpha-mannosidase-like 1; ER degradation enhancer, mannosidase alpha-like 1
products gene name :
EDEM1
other gene names :
EDEM1; EDEM1; EDEM; EDEM; KIAA0212
uniprot entry name :
EDEM1_HUMAN
reactivity :
Human
storage stability :
Store all reagents at 2-8 degree C
ncbi gi num :
7662002
ncbi acc num :
NP_055489.1
ncbi gb acc num :
NM_014674.2
uniprot acc num :
Q92611
ncbi mol weight :
73,768 Da
ncbi pathways :
Activation Of Chaperone Genes By XBP1(S) Pathway (530771); Activation Of Chaperones By IRE1alpha Pathway (105906); Asparagine N-linked Glycosylation Pathway (161013); Calnexin/calreticulin Cycle Pathway (187218); Diabetes Pathways (105902); Disease Pathway (530764); ER Quality Control Compartment (ERQC) Pathway (187219); Metabolism Of Proteins Pathway (106230); N-glycan Trimming In The ER And Calnexin/Calreticulin Cycle Pathway (187217); Post-translational Protein Modification Pathway (161012)
uniprot summary :
EDEM1: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It lacks mannosidase activity. Belongs to the glycosyl hydrolase 47 family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 3p26.1. Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane. Molecular Function: protein binding; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; misfolded protein binding; calcium ion binding. Biological Process: ER-associated protein catabolic process; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; protein folding; unfolded protein response; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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