catalog number :
MBS9331254
products type :
ELISA Kit
products full name :
Human Glutaminyl-tRNA synthetase, QARS ELISA Kit
products short name :
[glutaminyl-tRNA synthetase]
products name syn :
[Human Glutaminyl-tRNA synthetase (QARS) ELISA kit; GLNRS; PRO2195; glutamine tRNA ligase; glutamine-tRNA synthetase; glutaminyl-tRNA synthetase]
other names :
[glutamine--tRNA ligase isoform b; Glutamine--tRNA ligase; glutamine--tRNA ligase; glutamine-tRNA synthetase; glutaminyl-tRNA synthetase; Glutaminyl-tRNA synthetase; GlnRS]
products gene name :
[QARS]
other gene names :
[QARS; QARS; GLNRS; MSCCA; PRO2195; GlnRS]
uniprot entry name :
SYQ_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Body Fluids, Tissue Homogenates, Secretions Or Feces Samples. Assay Type: Quantitative Sandwich. Detection Range: 15.6 nmol/L-500 nmol/L. Sensitivity: 2.0 nmol/L.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PYD (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001259002.1
ncbi gb acc num :
NM_001272073.1
ncbi mol weight :
87,799 Da
ncbi pathways :
Aminoacyl-tRNA Biosynthesis Pathway (83030); Aminoacyl-tRNA Biosynthesis Pathway (424); Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway (413439); Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway (468360); Cytosolic TRNA Aminoacylation Pathway (105981); Gene Expression Pathway (105937); Mitochondrial TRNA Aminoacylation Pathway (105982); TRNA Aminoacylation Pathway (105980)
ncbi summary :
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
uniprot summary :
QARS: catalyzes the formation of L-glutaminyl-tRNA. Belongs to the class-I aminoacyl-tRNA synthetase family. Protein type: Translation; EC 6.1.1.18; Mitochondrial; Ligase. Chromosomal Location of Human Ortholog: 3p21.31. Cellular Component: mitochondrial matrix; cytoplasm; cytosol. Molecular Function: protein binding; glutamine-tRNA ligase activity; ATP binding. Biological Process: tRNA aminoacylation for protein translation; glutaminyl-tRNA aminoacylation; gene expression; brain development. Disease: Microcephaly, Progressive, With Seizures And Cerebral And Cerebellar Atrophy
size4 :
10x96-Strip-Wells