Mouse Protein disulfide-isomerase, P4HB ELISA Kit | MyBioSource MBS933098 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Protein disulfide-isomerase, P4HB ELISA Kit

catalog :

MBS933098

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS933098

products type :

ELISA Kit

products full name :

Mouse Protein disulfide-isomerase, P4HB ELISA Kit

products short name :

prolyl 4-hydroxylase, beta polypeptide

products name syn :

Mouse Protein disulfide-isomerase (P4HB) ELISA kit; DSI; ERBA2L; GIT; P4Hbeta; PDI; PDIA1; PHDB; PO4DB; PO4HB; PROHB; collagen prolyl 4-hydroxylase beta; glutathione-insulin transhydrogenase; procollagen-proline; 2-oxoglutarate 4-dioxygenase (proline 4; prolyl 4-hydroxylase; beta polypeptide

other names :

protein disulfide-isomerase; Protein disulfide-isomerase; protein disulfide-isomerase; p55; ER protein 59; protein disulfide isomerase; prolyl 4-hydroxylase subunit beta; cellular thyroid hormone-binding protein; endoplasmic reticulum resident protein 59; prolyl 4-hydroxylase, beta polypeptide; Cellular thyroid hormone-binding protein; Endoplasmic reticulum resident protein 59; ER protein 59; ERp59; Prolyl 4-hydroxylase subunit beta; p55

products gene name :

P4HB

other gene names :

P4hb; P4hb; PDI; Thbp; ERp59; Pdia1; Pdia1; PDI; ER protein 59; ERp59

uniprot entry name :

PDIA1_MOUSE

reactivity :

Mouse

sequence length :

509

specificity :

This assay has high sensitivity and excellent specificity for detection of Mouse P4HB. No significant cross-reactivity or interference between Mouse P4HB and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Detection Range: 0.312 ng/ml-20 ng/ml. Sensitivity: 0.078 ng/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul

ncbi gi num :

42415475

ncbi acc num :

NP_035162.1

ncbi gb acc num :

NM_011032.2

uniprot acc num :

P09103

ncbi mol weight :

57,058 Da

ncbi pathways :

Cellular Responses To Stress Pathway (971022); Chylomicron-mediated Lipid Transport Pathway (1001042); Collagen Biosynthesis And Modifying Enzymes Pathway (1001017); Collagen Formation Pathway (1001016); Detoxification Of Reactive Oxygen Species Pathway (970575); Disease Pathway (970606); Extracellular Matrix Organization Pathway (1001015); Hedgehog Ligand Biogenesis Pathway (1000756); Lipid Digestion, Mobilization, And Transport Pathway (1001038); Lipoprotein Metabolism Pathway (1001041)

uniprot summary :

PDIA1: This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Homodimer. Monomers and homotetramers may also occur. Also constitutes the structural subunit of prolyl 4-hydroxylase and of the microsomal triacylglycerol transfer protein MTTP in mammalian cells. Stabilizes both enzymes and retain them in the ER without contributing to the catalytic activity. Binds UBQLN1. Binds to CD4, and upon HIV-1 binding to the cell membrane, is part of a P4HB/PDI-CD4-CXCR4-gp120 complex. Belongs to the protein disulfide isomerase family. Protein type: Nuclear receptor co-regulator; Oxidoreductase; Endoplasmic reticulum; EC 5.3.4.1; Isomerase. Cellular Component: focal adhesion; membrane; endoplasmic reticulum; plasma membrane; ER-Golgi intermediate compartment. Molecular Function: enzyme binding; procollagen-proline 4-dioxygenase activity; protein heterodimerization activity; protein disulfide isomerase activity; isomerase activity; peptidyl-proline 4-dioxygenase activity. Biological Process: protein folding; cell redox homeostasis; peptidyl-proline hydroxylation to 4-hydroxy-L-proline

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage