Human Mothers against decapentaplegic homolog 5, SMAD5 ELISA Kit | MyBioSource MBS9330851 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Mothers against decapentaplegic homolog 5, SMAD5 ELISA Kit

catalog :

MBS9330851

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9330851

products type :

ELISA Kit

products full name :

Human Mothers against decapentaplegic homolog 5, SMAD5 ELISA Kit

products short name :

[SMAD family member 5]

products name syn :

[Human Mothers against decapentaplegic homolog 5 (SMAD5) ELISA kit; DKFZp781C1895; DKFZp781O1323; Dwfc; JV5-1; MADH5; MAD homolog 5; MAD; mothers against decapentaplegic homolog 5; SMA- and MAD-related protein 5; SMAD; mothers against DPP homolog 5; mothers against deca; SMAD family member 5]

other names :

[mothers against decapentaplegic homolog 5; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic homolog 5; SMA- and MAD-related protein 5; SMAD, mothers against DPP homolog 5; MAD, mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; SMAD family member 5; JV5-1; SMAD family member 5; SMAD 5; Smad5; hSmad5]

products gene name :

[SMAD5]

other gene names :

[SMAD5; SMAD5; DWFC; JV5-1; MADH5; MADH5; MAD homolog 5; Mothers against DPP homolog 5; SMAD 5; Smad5; hSmad5]

uniprot entry name :

SMAD5_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma and Tissue Homogenate. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml. Assay Type: Sandwich

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SMAD5 (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.

ncbi gi num :

47778929

ncbi acc num :

NP_001001419.1

ncbi gb acc num :

NM_001001419.2

uniprot acc num :

Q99717

ncbi mol weight :

52,258 Da

ncbi pathways :

ALK1 Signaling Events Pathway (137968); ALK2 Signaling Events Pathway (137983); BMP Receptor Signaling Pathway (137948); Id Signaling Pathway (198871); Signal Transduction Pathway (477114); Signaling By BMP Pathway (106336); TGF Beta Signaling Pathway (198810); TGF-beta Signaling Pathway (83064); TGF-beta Signaling Pathway (475)

ncbi summary :

The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

uniprot summary :

SMAD5: transcription factor phosphorylated and activated by bone morphogenetic protein receptor kinases. Phosphorylated Smads dimerize with collaborating Smad4 and are translocated into the nucleus, where they regulate transcription of target genes. Participates in a wide range of critical processes including morphogenesis, cell-fate determination, proliferation, differentiation and apoptosis. Protein type: DNA-binding; Transcription, coactivator/corepressor. Chromosomal Location of Human Ortholog: 5q31. Cellular Component: nucleoplasm; transcription factor complex; protein complex; cytoplasm; integral to membrane; intracellular; cytosol; nucleus. Molecular Function: protein binding; ubiquitin protein ligase binding; metal ion binding; receptor signaling protein activity; transcription factor activity; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity. Biological Process: Mullerian duct regression; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; embryonic pattern specification; signal transduction; protein amino acid phosphorylation; germ cell development; BMP signaling pathway; positive regulation of osteoblast differentiation; ureteric bud development; cartilage development; transforming growth factor beta receptor signaling pathway; erythrocyte differentiation; cardiac muscle contraction; osteoblast fate commitment

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095