Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3, SMARCD3 ELISA Kit | MyBioSource MBS9330761 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3, SMARCD3 ELISA Kit

catalog :

MBS9330761

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9330761

products type :

ELISA Kit

products full name :

Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3, SMARCD3 ELISA Kit

products short name :

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3

products name syn :

Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (SMARCD3) ELISA kit; BAF60C; CRACD3; MGC111010; Rsc6p; 60kDa BRG-1/Brm associated factor subunit c; SWI/SNF complex 60 kDa subunit C; SWI/SNF related; matrix associated; actin dependent regulator of chromatin; subfamily d; SWI/SNF related; matrix associated; actin dependent regulator of chromatin; subfamily d; member 3

other names :

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 isoform 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3; Swp73-like protein; BRG1-associated factor 60C; SWI/SNF complex 60 kDa subunit C; chromatin remodeling complex BAF60C subunit; 60 kDa BRG-1/Brm-associated factor subunit C; mammalian chromatin remodeling complex BRG1-associated factor 60C; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3, isoform 1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3; 60 kDa BRG-1/Brm-associated factor subunit C; BRG1-associated factor 60C; BAF60C

products gene name :

SMARCD3

other gene names :

SMARCD3; SMARCD3; Rsc6p; BAF60C; CRACD3; BAF60C; BAF60C

uniprot entry name :

SMRD3_HUMAN

reactivity :

Human

storage stability :

Store all reagents at 2-8 degree C

ncbi gi num :

51477702

ncbi acc num :

NP_001003801.1

ncbi gb acc num :

NM_001003801.1

uniprot acc num :

Q6STE5

ncbi mol weight :

55,016 Da

ncbi pathways :

BMAL1:CLOCK/NPAS2 Activates Circadian Expression Pathway (477138); Circadian Clock Pathway (187173); Circadian Repression Of Expression By REV-ERBA Pathway (576259); Developmental Biology Pathway (477129); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Gene Expression Pathway (105937); Generic Transcription Pathway (105938); LKB1 Signaling Events Pathway (137957); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976)

ncbi summary :

The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

uniprot summary :

SMARCD3: Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. Stimulates nuclear receptor mediated transcription. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron- specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post- mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. Belongs to the SMARCD family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator. Chromosomal Location of Human Ortholog: 7q35-q36. Cellular Component: nucleoplasm; SWI/SNF complex; cytoplasm; nuclear chromatin; nucleus. Molecular Function: ligand-dependent nuclear receptor binding; protein binding; ligand-dependent nuclear receptor transcription coactivator activity; transcription coactivator activity; transcription factor binding; receptor binding; nuclear hormone receptor binding. Biological Process: chromatin remodeling; regulation of transcription from RNA polymerase II promoter; positive regulation of neuroblast proliferation; muscle cell differentiation; nucleosome disassembly; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of protein binding; cellular lipid metabolic process

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage