catalog number :
MBS9330676
products type :
ELISA Kit
products full name :
Human Folate receptor gamma, FOLR3 ELISA Kit
products short name :
[folate receptor 3 (gamma)]
products name syn :
[Human Folate receptor gamma (FOLR3) ELISA kit; FR-G; FR-gamma; gamma-hFR; folate receptor 3; folate receptor 3 (gamma)]
other names :
[folate receptor gamma; Folate receptor gamma; folate receptor gamma; folate receptor 3 (gamma); Folate receptor 3]
products gene name :
[FOLR3]
other gene names :
[FOLR3; FOLR3; FR-G; FR-gamma; gamma-hFR; FR-gamma]
uniprot entry name :
FOLR3_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of FOLR3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_000795.2
ncbi gb acc num :
NM_000804.2
ncbi mol weight :
27,638 Da
ncbi pathways :
Endocytosis Pathway (102279); Endocytosis Pathway (102181)
ncbi summary :
This gene encodes a member of the folate receptor (FOLR) family, members of which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This gene includes two polymorphic variants; the shorter one has two base deletion in the CDS, resulting in a truncated polypeptide, compared to the longer one. Both protein products are constitutively secreted in hematopoietic tissues and are potential serum marker for certain hematopoietic malignancies. The longer protein has a 71% and 79% sequence homology with the FOLR1 and FOLR2 proteins, respectively. [provided by RefSeq, Jul 2008]
uniprot summary :
FOLR3: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Isoform Short does not bind folate. Belongs to the folate receptor family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 11q13. Cellular Component: extrinsic to membrane; membrane; extracellular region. Molecular Function: folic acid binding. Biological Process: folic acid transport
size4 :
10x96-Strip-Wells