ELISA/assay

Human GRIP and coiled-coil domain-containing protein 2, GCC2 ELISA Kit

MBS9330667

48-Strip-Wells

470 USD

ELISA Kit

Human GRIP and coiled-coil domain-containing protein 2, GCC2 ELISA Kit

[GRIP and coiled-coil domain containing 2]

[Human GRIP and coiled-coil domain-containing protein 2 (GCC2) ELISA kit; GCC185; KIAA0336; RANBP2L4; REN53; CLL-associated antigen KW-11; CTCL tumor antigen se1-1; GCC protein; 185-kD; GRIP and coiled-coil domain-containing 2; Golgi coiled-coil protein GCC185; Ran-binding pro; GRIP and coiled-coil domain containing 2]

[GRIP and coiled-coil domain-containing protein 2; GRIP and coiled-coil domain-containing protein 2; GRIP and coiled-coil domain-containing protein 2; GCC protein, 185-kD; CTCL tumor antigen se1-1; CLL-associated antigen KW-11; Ran-binding protein 2-like 4; Golgi coiled-coil protein GCC185; 185 kDa Golgi coiled-coil protein; renal carcinoma antigen NY-REN-53; GRIP and coiled-coil domain containing 2; 185 kDa Golgi coiled-coil protein; GCC185; CLL-associated antigen KW-11; CTCL tumor antigen se1-1; Ran-binding protein 2-like 4; RanBP2L4; Renal carcinoma antigen NY-REN-53]

[GCC2]

[GCC2; GCC2; REN53; GCC185; RANBP2L4; KIAA0336; RANBP2L4; GCC185; RanBP2L4]

GCC2_HUMAN

Human

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

Intra-assay Precision: Intra-assay CV (%) are less than 15%. Inter-assay Precision: Inter-assay CV (?) are less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of GCA (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

31563507

NP_852118.1

NM_181453.3

Q8IWJ2

195,910 Da

The protein encoded by this gene is a peripheral membrane protein localized to the trans-Golgi network. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

GCC2: Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, peripheral. Chromosomal Location of Human Ortholog: 2q12.3. Cellular Component: nucleoplasm; Golgi apparatus; membrane; cytoplasm; trans-Golgi network; nucleus. Molecular Function: identical protein binding; protein binding. Biological Process: microtubule organizing center organization and biogenesis; protein targeting to lysosome; protein localization in Golgi apparatus; Golgi to plasma membrane protein transport; protein targeting to Golgi; retrograde transport, endosome to Golgi

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095