catalog number :
MBS9330645
products type :
ELISA Kit
products full name :
Mouse DNA fragmentation factor subunit beta, DFFB ELISA Kit
products short name :
[DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)]
products name syn :
[Mouse DNA fragmentation factor subunit beta (DFFB) ELISA kit; RP13-531C17.1; CAD; CPAN; DFF-40; DFF2; DFF40; DNA fragmentation factor; 40 kD; beta polypeptide; caspase-activated deoxyribonuclease; caspase-activated nuclease; DNA fragmentation factor; 40kDa; beta polypeptide (caspase-activated DNase)]
other names :
[DNA fragmentation factor subunit beta; DNA fragmentation factor subunit beta; DNA fragmentation factor subunit beta; DFF-40; caspase-activated DNase; caspase-activated deoxyribonuclease; DNA fragmentation factor 40 kDa subunit; DNase inhibited by DNA fragmentation factor; DNA fragmentation factor, 40 kD, beta subunit; DNA fragmentation factor, beta subunit; Caspase-activated deoxyribonuclease; CAD; Caspase-activated DNase; DNA fragmentation factor 40 kDa subunit; DFF-40]
products gene name :
[DFFB]
other gene names :
[Dffb; Dffb; CAD; CPAN; 40kDa; DFF40; Didff; 5730477D02Rik; Cad; CAD; Caspase-activated DNase; DFF-40]
uniprot entry name :
DFFB_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of DFFB (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_031885.3
ncbi gb acc num :
NM_007859.4
ncbi mol weight :
39,449 Da
ncbi pathways :
Activation Of DNA Fragmentation Factor Pathway (574618); Apoptosis Pathway (198339); Apoptosis Pathway (83257); Apoptosis Pathway (470); Apoptosis Pathway (574586); Apoptosis Induced DNA Fragmentation Pathway (574617); Apoptosis Signaling Pathway (522973); Apoptotic Execution Phase Pathway (574612); FAS Pathway And Stress Induction Of HSP Regulation (198421)
uniprot summary :
DFFB: Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. 4 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.-.-.-; Apoptosis; Deoxyribonuclease. Cellular Component: cytoplasm; nuclear chromatin; nucleolus; intracellular; cytosol; nucleus. Molecular Function: protein binding; nuclease activity; enzyme binding; DNA binding; hydrolase activity; deoxyribonuclease activity; GPI-anchor transamidase activity. Biological Process: apoptosis; DNA fragmentation during apoptosis; apoptotic chromosome condensation
size4 :
10x96-Strip-Wells