product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Regulator of telomere elongation helicase 1, RTEL1 ELISA Kit
catalog :
MBS9330144
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
product information
catalog number :
MBS9330144
products type :
ELISA Kit
products full name :
Human Regulator of telomere elongation helicase 1, RTEL1 ELISA Kit
products short name :
[regulator of telomere elongation helicase 1]
products name syn :
[Human Regulator of telomere elongation helicase 1 (RTEL1) ELISA kit; RP4-583P15.2; C20orf41; DKFZp434C013; KIAA1088; NHL; RTEL; bK3184A7.3; regulator of telomere length; regulator of telomere elongation helicase 1]
other names :
[regulator of telomere elongation helicase 1 isoform 3; Regulator of telomere elongation helicase 1; regulator of telomere elongation helicase 1; regulator of telomere length; regulator of telomere elongation helicase 1; Novel helicase-like]
products gene name :
[RTEL1]
other gene names :
[RTEL1; RTEL1; NHL; RTEL; DKCA4; DKCB5; C20orf41; C20orf41; KIAA1088; NHL]
uniprot entry name :
RTEL1_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RTEL1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
545688900
ncbi acc num :
NP_001269938.1
ncbi gb acc num :
NM_001283009.1
uniprot acc num :
Q9NZ71
ncbi mol weight :
133,683 Da
ncbi summary :
This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]
uniprot summary :
RTEL1: ATP-dependent DNA helicase required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologous recombination by promoting the disassembly of D loop recombination intermediates. Also required to regulate telomere length; probably due to its anti-recombinase function. Belongs to the helicase family. RAD3/XPD subfamily. 8 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.6.4.12; DNA repair, damage; Helicase. Chromosomal Location of Human Ortholog: 20q13.3. Cellular Component: nucleus. Molecular Function: ATP-dependent DNA helicase activity; protein binding; DNA binding; 4 iron, 4 sulfur cluster binding; metal ion binding; ATP binding. Biological Process: DNA repair; telomere maintenance; DNA duplex unwinding. Disease: Dyskeratosis Congenita, Autosomal Recessive, 5; Pulmonary Fibrosis And/or Bone Marrow Failure, Telomere-related, 3
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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