catalog number :
MBS9329634
products type :
ELISA Kit
products full name :
Mouse Rap guanine nucleotide exchange factor 3, RAPGEF3 ELISA Kit
products short name :
[Rap guanine nucleotide exchange factor (GEF) 3]
products name syn :
[Mouse Rap guanine nucleotide exchange factor 3 (RAPGEF3) ELISA kit; CAMP-GEFI; EPAC; EPAC1; HSU79275; MGC21410; bcm910; 9330170P05Rik; Rap guanine nucleotide exchange factor 3; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP; exchange protein directl; Rap guanine nucleotide exchange factor (GEF) 3]
other names :
[rap guanine nucleotide exchange factor 3 isoform 1; Rap guanine nucleotide exchange factor 3; rap guanine nucleotide exchange factor 3; cAMP-GEFI; exchange protein directly activated by cAMP 1; cAMP-regulated guanine nucleotide exchange factor I; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP; Rap guanine nucleotide exchange factor (GEF) 3; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; EPAC 1; cAMP-regulated guanine nucleotide exchange factor I; cAMP-GEFI]
products gene name :
[RAPGEF3]
other gene names :
[Rapgef3; Rapgef3; Epac; Epac1; 2310016P22Rik; 9330170P05Rik; Epac; Epac1; EPAC 1; cAMP-GEFI]
uniprot entry name :
RPGF3_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 3.12ng/ml-100ng/ml. Sensitivity: 1.0ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of RAP3A (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001171281.1
ncbi gb acc num :
NM_001177810.1
ncbi mol weight :
103,533 Da
ncbi pathways :
Adaptive Immune System Pathway (575096); Hemostasis Pathway (575479); Immune System Pathway (575095); Integration Of Energy Metabolism Pathway (574807); Integrin AlphaIIb Beta3 Signaling Pathway (575476); Integrin Cell Surface Interactions Pathway (575475); Leukocyte Transendothelial Migration Pathway (83280); Leukocyte Transendothelial Migration Pathway (494); Long-term Potentiation Pathway (83282); Long-term Potentiation Pathway (496)
uniprot summary :
Epac1: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney. 2 isoforms of the human protein are produced by alternative splicing. Protein type: GEFs; GEFs, misc. Cellular Component: membrane; cytoplasm; intracellular; cAMP-dependent protein kinase complex. Molecular Function: Rap guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; nucleotide binding; cAMP-dependent protein kinase regulator activity; cAMP binding. Biological Process: positive regulation of syncytium formation by plasma membrane fusion; positive regulation of protein export from nucleus; regulation of small GTPase mediated signal transduction; positive regulation of angiogenesis; regulation of protein amino acid phosphorylation; small GTPase mediated signal transduction; positive regulation of stress fiber formation; angiogenesis; positive regulation of peptidyl-serine phosphorylation; Rap protein signal transduction; positive regulation of GTPase activity
size4 :
10x96-Strip-Wells