Human Serine/threonine-protein kinase 4, STK4 ELISA Kit | MyBioSource MBS9329504 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Serine/threonine-protein kinase 4, STK4 ELISA Kit

catalog :

MBS9329504

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9329504

products type :

ELISA Kit

products full name :

Human Serine/threonine-protein kinase 4, STK4 ELISA Kit

products short name :

[serine/threonine kinase 4]

products name syn :

[Human Serine/threonine-protein kinase 4 (STK4) ELISA kit; DKFZp686A2068; KRS2; MST1; YSK3; dJ211D12.2 (serine/threonine kinase 4 (MST1; KRS2) ) ; kinase responsive to stress 2; mammalian sterile 20-like 1; yeast Ste20-like; serine/threonine kinase 4]

other names :

[serine/threonine-protein kinase 4; Serine/threonine-protein kinase 4; serine/threonine-protein kinase 4; MST-1; STE20-like kinase MST1; mammalian sterile 20-like 1; kinase responsive to stress 2; mammalian STE20-like protein kinase 1; serine/threonine-protein kinase Krs-2; dJ211D12.2 (serine/threonine kinase 4 (MST1, KRS2)); serine/threonine kinase 4; Mammalian STE20-like protein kinase 1; MST-1; STE20-like kinase MST1; Serine/threonine-protein kinase Krs-2Cleaved into the following 2 chains:Serine/threonine-protein kinase 4 37kDa subunit; MST1/N; Serine/threonine-protein kinase 4 18kDa subunit; MST1/C]

products gene name :

[STK4]

other gene names :

[STK4; STK4; KRS2; MST1; YSK3; TIIAC; KRS2; MST1; MST-1; MST1/N; MST1/C]

uniprot entry name :

STK4_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of STK4 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

5454096

ncbi acc num :

NP_006273.1

ncbi gb acc num :

NM_006282.2

uniprot acc num :

Q13043

ncbi mol weight :

55,630 Da

ncbi pathways :

MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Non-small Cell Lung Cancer Pathway (83119); Non-small Cell Lung Cancer Pathway (531); Pathways In Cancer (83105); Signal Transduction Pathway (477114); Signaling By Hippo Pathway (576275)

ncbi summary :

The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq, Jul 2008]

uniprot summary :

MST1: a protein kinase of the STE20 family. Proteolytically activated by caspase during apoptosis. Activated by apoptotic signals as well as other stress conditions. Full activation requires both phosphorylation and caspase-mediated cleavage. Phosphorylation at serine 327 of Mst1, which is close to the caspase-3 recognition site, inhibits caspase-mediated cleavage. Protein type: Protein kinase, STE; Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Autophagy; STE group; STE20 family; MST subfamily. Chromosomal Location of Human Ortholog: 20q11.2-q13.2. Cellular Component: nucleoplasm; cytoplasm; nucleus; cytosol. Molecular Function: protein dimerization activity; protein serine/threonine kinase activity; protein serine/threonine kinase activator activity; identical protein binding; protein binding; protein homodimerization activity; magnesium ion binding; transcription factor binding; ATP binding; receptor signaling protein serine/threonine kinase activity. Biological Process: central nervous system development; positive regulation of protein binding; positive regulation of apoptosis; apoptosis; protein amino acid autophosphorylation; cell morphogenesis; negative regulation of organ growth; signal transduction; protein amino acid phosphorylation; keratinocyte differentiation; patterning of blood vessels; negative regulation of cell proliferation; peptidyl-serine phosphorylation; positive regulation of fat cell differentiation; neural tube formation. Disease: T-cell Immunodeficiency, Recurrent Infections, And Autoimmunity With Or Without Cardiac Malformations

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage