Human Tyrosine-protein kinase Fes/Fps, FES ELISA Kit | MyBioSource MBS9329305 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Tyrosine-protein kinase Fes/Fps, FES ELISA Kit

catalog :

MBS9329305

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9329305

products type :

ELISA Kit

products full name :

Human Tyrosine-protein kinase Fes/Fps, FES ELISA Kit

products short name :

[feline sarcoma oncogene]

products name syn :

[Human Tyrosine-protein kinase Fes/Fps (FES) ELISA kit; FPS; Oncogene FES; feline sarcoma virus; c-fes/fps protein; feline sarcoma (Snyder-Theilen) viral (v-fes) /Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog; proto-oncogene tyrosine-protein; feline sarcoma oncogene]

other names :

[tyrosine-protein kinase Fes/Fps isoform 2; Tyrosine-protein kinase Fes/Fps; tyrosine-protein kinase Fes/Fps; p93c-fes; proto-oncogene c-Fes; proto-oncogene c-Fps; feline sarcoma oncogene; Oncogene FES, feline sarcoma virus; proto-oncogene tyrosine-protein kinase Fes/Fps; feline sarcoma/Fujinami avian sarcoma oncogene homolog; feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog; FES proto-oncogene, tyrosine kinase; Feline sarcoma/Fujinami avian sarcoma oncogene homolog; Proto-oncogene c-Fes; Proto-oncogene c-Fps; p93c-fes]

products gene name :

[FES]

other gene names :

[FES; FES; FPS; FPS]

uniprot entry name :

FES_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Human Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of FER (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

ncbi gi num :

219842230

ncbi acc num :

NP_001137255.1

ncbi gb acc num :

NM_001143783.1

uniprot acc num :

P07332

ncbi mol weight :

93,497 Da

ncbi pathways :

Angiopoietin Receptor Tie2-mediated Signaling Pathway (137917); Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (105688); CRMPs In Sema3A Signaling Pathway (119525); Developmental Biology Pathway (477129); IL-3 Signaling Pathway (198881); IL-4 Signaling Pathway (198760); IL-6 Signaling Pathway (198864); IL4-mediated Signaling Events Pathway (137933)

ncbi summary :

This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009]

uniprot summary :

Fes: a non-receptor tyrosine kinase of the Fer family. Appears to be involved in normal hematopoiesis as well as the development of acute promyelocytic leukemia. Contains one SH2 and one FCH domain. Four LOF point mutations seen in colorectal cancer. Orthologous to v-fes from feline leukemia virus and v-fps from avian transforming virus. Mutant forms are angiogenic. Promotes survival during differentiation, and may act both to promote and inhibit tumors. May be disrupted in the t(15q+;17q-) found in acute promyelocytic leukemia, but the breakpoint does not occur within the gene. Protein type: Oncoprotein; Protein kinase, TK; Kinase, protein; Tumor suppressor; EC 2.7.10.2; Protein kinase, tyrosine (non-receptor); TK group; Fer family. Chromosomal Location of Human Ortholog: 15q26.1. Cellular Component: microtubule cytoskeleton; Golgi apparatus; extrinsic to internal side of plasma membrane; focal adhesion; cytoplasmic membrane-bound vesicle; cytoplasm; cytoplasmic vesicle; cytosol. Molecular Function: protein binding; protein-tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; phosphoinositide binding; ATP binding. Biological Process: regulation of mast cell degranulation; regulation of cell adhesion; epidermal growth factor receptor signaling pathway; axon guidance; cell migration; peptidyl-tyrosine phosphorylation; positive regulation of myeloid cell differentiation; protein amino acid autophosphorylation; multicellular organismal development; positive regulation of microtubule polymerization; chemotaxis; protein amino acid phosphorylation; regulation of cell proliferation; cell proliferation; regulation of cell shape; regulation of cell differentiation; innate immune response

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095