catalog number :
MBS9329169
products type :
ELISA Kit
products full name :
Human V-type proton ATPase 16 kDa proteolipid subunit, ATP6V0C ELISA Kit
products short name :
[ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c]
products name syn :
[Human V-type proton ATPase 16 kDa proteolipid subunit (ATP6V0C) ELISA kit; ATP6C; ATP6L; ATPL; VATL; Vma3; ATPase; H+ transporting; lysosomal; V0 subunit c; H (+) -transporting two-sector ATPase; 16 kDa subunit; V-ATPase subunit c; vacuolar ATP synthase 16 kDa proteolipid subun; ATPase; H+ transporting; lysosomal 16kDa; V0 subunit c]
other names :
[V-type proton ATPase 16 kDa proteolipid subunit; V-type proton ATPase 16 kDa proteolipid subunit; V-type proton ATPase 16 kDa proteolipid subunit; V-ATPase 16 kDa proteolipid subunit; vacuolar H+ ATPase proton channel subunit; vacuolar proton pump 16 kDa proteolipid subunit; vacuolar ATP synthase 16 kDa proteolipid subunit; H(+)-transporting two-sector ATPase, 16 kDa subunit; ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c; Vacuolar proton pump 16 kDa proteolipid subunit]
products gene name :
[ATP6V0C]
other gene names :
[ATP6V0C; ATP6V0C; ATPL; VATL; VPPC; Vma3; ATP6C; ATP6L; ATP6C; ATP6L; ATPL; V-ATPase 16 kDa proteolipid subunit]
uniprot entry name :
VATL_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Mouse Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) are less than 15%. Inter-assay Precision: Inter-assay CV (?) are less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of ATP6V0A4 (hereafter termed "analyte") in undiluted original Mouse body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001185498.1
ncbi gb acc num :
NM_001198569.1
ncbi mol weight :
15,736 Da
ncbi pathways :
Collecting Duct Acid Secretion Pathway (147586); Collecting Duct Acid Secretion Pathway (147560); Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway (83102); Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway (515); Insulin Receptor Recycling Pathway (106438); Iron Uptake And Transport Pathway (187191); Lysosome Pathway (99052); Lysosome Pathway (96865); Oxidative Phosphorylation Pathway (82942); Oxidative Phosphorylation Pathway (303)
ncbi summary :
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17. [provided by RefSeq, Nov 2010]
uniprot summary :
ATP6V0C: Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Belongs to the V-ATPase proteolipid subunit family. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, ion channel; Transporter, iron; Transporter. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: phagocytic vesicle membrane; focal adhesion; lysosomal membrane; integral to membrane; endosome membrane. Molecular Function: protein binding; ubiquitin protein ligase binding; hydrogen ion transporting ATP synthase activity, rotational mechanism; hydrogen ion transporting ATPase activity, rotational mechanism. Biological Process: interaction with host; proton transport; viral reproduction; cellular iron ion homeostasis; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; transferrin transport; transmembrane transport; positive regulation of Wnt receptor signaling pathway
size4 :
10x96-Strip-Wells