Human Nuclear receptor coactivator 4, NCOA4 ELISA Kit | MyBioSource MBS9329141 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Nuclear receptor coactivator 4, NCOA4 ELISA Kit

catalog :

MBS9329141

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9329141

products type :

ELISA Kit

products full name :

Human Nuclear receptor coactivator 4, NCOA4 ELISA Kit

products short name :

[nuclear receptor coactivator 4]

products name syn :

[Human Nuclear receptor coactivator 4 (NCOA4) ELISA kit; RP11-481A12.4; ARA70; DKFZp762E1112; ELE1; PTC3; RFG; RET-activating gene ELE1; androgen receptor coactivator; 70-kD; papillary thyroid carcinoma 3; ret fused; nuclear receptor coactivator 4]

other names :

[nuclear receptor coactivator 4 isoform 1; Nuclear receptor coactivator 4; nuclear receptor coactivator 4; NCoA-4; ret fused; 70 kDa AR-activator; RET-activating gene ELE1; 70 kDa androgen receptor coactivator; androgen receptor-associated protein of 70 kDa; nuclear receptor coactivator 4; Androgen receptor coactivator 70 kDa protein; 70 kDa AR-activator; 70 kDa androgen receptor coactivator; Androgen receptor-associated protein of 70 kDa; Ret-activating protein ELE1]

products gene name :

[NCOA4]

other gene names :

[NCOA4; NCOA4; RFG; ELE1; PTC3; ARA70; ARA70; ELE1; RFG; NCoA-4; 70 kDa AR-activator; 70 kDa androgen receptor coactivator]

uniprot entry name :

NCOA4_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Human Body Fluids, Tissue Homogenates, Secretions Or Feces Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of NASP (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

223890278

ncbi acc num :

NP_001138732.1

ncbi gb acc num :

NM_001145260.1

uniprot acc num :

Q13772

ncbi mol weight :

69,726 Da

ncbi pathways :

Androgen Receptor Signaling Pathway (198806); Coregulation Of Androgen Receptor Activity Pathway (138085); Diurnally Regulated Genes With Circadian Orthologs Pathway (198813); Pathways In Cancer (83105); Thyroid Cancer Pathway (83112); Thyroid Cancer Pathway (524)

ncbi summary :

This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14. [provided by RefSeq, Feb 2009]

uniprot summary :

NCOA4: Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma. Defects in NCOA4 are a cause of thyroid papillary carcinoma (TPC). TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. A chromosomal aberration involving NCOA4 is found in thyroid papillary carcinomas. Inversion inv(10)(q11.2;q11.2) generates the RET/NCOA4 (PTC3) oncogene that has been found in sporadic and radiation-associated post-Chernobyl thyroid papillary carcinomas. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Oncoprotein; Nuclear receptor co-regulator. Chromosomal Location of Human Ortholog: 10q11.2. Cellular Component: nucleus. Molecular Function: androgen receptor binding; transcription coactivator activity. Biological Process: transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; androgen receptor signaling pathway; male gonad development; response to hormone stimulus. Disease: Thyroid Carcinoma, Papillary

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095